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VAMP8 抗体

VAMP8 适用: 人, 大鼠, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7120762
发货至: 中国
  • 抗原 See all VAMP8 抗体
    VAMP8 (Vesicle-Associated Membrane Protein 8 (Endobrevin) (VAMP8))
    适用
    • 44
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    人, 大鼠, 小鼠
    宿主
    • 39
    • 5
    克隆类型
    • 33
    • 11
    多克隆
    标记
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    This VAMP8 antibody is un-conjugated
    应用范围
    • 16
    • 14
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    • 8
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    Western Blotting (WB), ELISA
    纯化方法
    Immunogen affinity purified
    纯度
    ≥95 % as determined by SDS-PAGE
    免疫原
    vesicle-associated membrane protein 8(endobrevin)
    亚型
    IgG
    Top Product
    Discover our top product VAMP8 Primary Antibody
  • 应用备注
    WB: 1:200-1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    有效期
    12 months
  • 抗原
    VAMP8 (Vesicle-Associated Membrane Protein 8 (Endobrevin) (VAMP8))
    别名
    VAMP8 (VAMP8 产品)
    别名
    vamp8 antibody, EDB antibody, VAMP-8 antibody, AU041171 antibody, Edb antibody, endobrevin antibody, wu:fa18d07 antibody, zgc:56588 antibody, vesicle associated membrane protein 8 antibody, vesicle-associated membrane protein 8 (endobrevin) antibody, vesicle-associated membrane protein 8 antibody, vamp8 antibody, VAMP8 antibody, Vamp8 antibody
    背景
    Synonyms:EDB, Endobrevin, VAMP 8, VAMP8 Background:SNAREs, soluble N-ethylmaleimide-sensitive factor-attachment protein receptors, are essential proteins for fusion of cellular membranes. SNAREs localized on opposing membranes assemble to form a trans-SNARE complex, an extended, parallel four alpha-helical bundle that drives membrane fusion. VAMP8 is a SNARE involved in autophagy through the direct control of autophagosome membrane fusion with the lysososome membrane via its interaction with the STX17-SNAP29 binary t-SNARE complex(PubMed:23217709, PubMed:25686604). Also required for dense-granule secretion in platelets(PubMed:12130530). Plays also a role in regulated enzyme secretion in pancreatic acinar cells(By similarity). Involved in the abscission of the midbody during cell division, which leads to completely separate daughter cells(By similarity). Involved in the homotypic fusion of early and late endosomes(By similarity).
    分子量
    15 kDa
    基因ID
    8673
    UniProt
    Q9BV40
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