VPS25 antibody, CG14750 antibody, Dmel\\CG14750 antibody, ESCRT-I antibody, ESCRT-II antibody, dVps25 antibody, l(2)44Db antibody, l(2)k08904 antibody, vps25 antibody, GB16268 antibody, derp9 antibody, eap20 antibody, fap20 antibody, DDBDRAFT_0189483 antibody, DDBDRAFT_0234026 antibody, DDB_0189483 antibody, DDB_0234026 antibody, 1110020N13Rik antibody, AW107467 antibody, D11Wsu68e antibody, im:6898134 antibody, zgc:162560 antibody, DERP9 antibody, EAP20 antibody, FAP20 antibody, vacuolar protein sorting 25 homolog antibody, vacuolar protein sorting 25 homolog (S. cerevisiae) pseudogene antibody, vacuolar protein sorting-associated protein 25 antibody, WNK lysine deficient protein kinase 4 antibody, Vacuolar protein sorting 25 antibody, vacuolar protein-sorting-associated protein 25 antibody, vacuolar protein sorting 25 homolog L homeolog antibody, vacuolar protein sorting 25 antibody, vacuolar protein sorting 25 homolog (S. cerevisiae) antibody, E2F/DP family winged-helix DNA-binding domain-containing protein antibody, VPS25 antibody, LOC459431 antibody, CpipJ_CPIJ010292 antibody, WNK4 antibody, Vps25 antibody, LOC412381 antibody, vps25.L antibody, vps25 antibody
背景
Synonyms:DERP9, EAP20, ESCRT II complex subunit VPS25, FAP20, hVps25, VPS25 Background:Component of the ESCRT-II complex(endosomal sorting complex required for transport II), which is required for multivesicular body(MVB) formation and sorting of endosomal cargo proteins into MVBs. The MVB pathway mediates delivery of transmembrane proteins into the lumen of the lysosome for degradation. The ESCRT-II complex is probably involved in the recruitment of the ESCRT-III complex. The ESCRT-II complex may also play a role in transcription regulation, possibly via its interaction with ELL. The ESCRT-II complex may be involved in facilitating the budding of certain RNA viruses.