VPS41 抗体
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- 抗原 See all VPS41 抗体
- VPS41 (Vacuolar Protein Sorting 41 Homolog (VPS41))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This VPS41 antibody is un-conjugated
- 应用范围
- ELISA, Western Blotting (WB), Immunofluorescence (IF)
- 纯化方法
- Immunogen affinity purified
- 纯度
- ≥95 % as determined by SDS-PAGE
- 免疫原
- vacuolar protein sorting 41 homolog(S. cerevisiae)
- 亚型
- IgG
- Top Product
- Discover our top product VPS41 Primary Antibody
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anti-Vacuolar Protein Sorting 41 Homolog (VPS41) antibody
VPS41 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Vacuolar Protein Sorting 41 Homolog (VPS41) (AA 755-853) antibodyVPS41 适用: 人 ELISA, WB 宿主: 小鼠 Polyclonal unconjugated
anti-Vacuolar Protein Sorting 41 Homolog (VPS41) (Internal Region) antibodyVerified VPS41 适用: 人 ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Vacuolar Protein Sorting 41 Homolog (VPS41) (AA 467-516) antibodyVPS41 适用: 人, 小鼠, 大鼠, 犬, 兔, Cow, 豚鼠, 马 WB 宿主: 兔 Polyclonal unconjugated
anti-Vacuolar Protein Sorting 41 Homolog (VPS41) (N-Term) antibodyVPS41 适用: 人, 小鼠, 大鼠, 犬, 兔, Cow, 豚鼠, 马, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
anti-Vacuolar Protein Sorting 41 Homolog (VPS41) (Middle Region) antibodyVPS41 适用: 人, 小鼠, 大鼠, 犬, 兔, Cow, 豚鼠, 马 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB: 1:200-1:1000, IF: 1:10-1:100
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
- 有效期
- 12 months
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- 抗原
- VPS41 (Vacuolar Protein Sorting 41 Homolog (VPS41))
- 别名
- VPS41 (VPS41 产品)
- 别名
- AI317346 antibody, Vam2 antibody, mVam2 antibody, HVPS41 antibody, HVSP41 antibody, hVps41p antibody, RGD1560511 antibody, ATVAM2 antibody, ATVPS41 antibody, T23G18.5 antibody, T23G18_5 antibody, VACUOLAR PROTEIN SORTING 41 antibody, VAM2 antibody, ZIGZAG SUPPRESSOR 2 antibody, ZIP2 antibody, vacuolar protein sorting 41 antibody, Vacuolar assembly protein VPS41 homolog antibody, VPS41, HOPS complex subunit antibody, vacuolar protein sorting 41 antibody, vacuolar protein sorting 41, putative antibody, Vacuolar protein sorting-associated protein 41 homolog antibody, VPS41 HOPS complex subunit antibody, Bm1_34430 antibody, VPS41 antibody, CNI02550 antibody, CC1G_08871 antibody, MCYG_00680 antibody, VDBG_03430 antibody, MGYG_01292 antibody, CGB_H3560C antibody, vps-41 antibody, Vps41 antibody
- 背景
- Synonyms:HVPS41, hVps41p, HVSP41, S53, VPS41 Background:Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act in part as a core component of the putative HOPS endosomal tethering complex is proposed to be involved in the Rab5-to-Rab7 endosome conversion probably implicating MON1A/B, and via binding SNAREs and SNARE complexes to mediate tethering and docking events during SNARE-mediated membrane fusion. The HOPS complex is proposed to be recruited to Rab7 on the late endosomal membrane and to regulate late endocytic, phagocytic and autophagic traffic towards lysosomes(PubMed:23351085). Involved in homotypic vesicle fusions between late endosomes and in heterotypic fusions between late endosomes and lysosomes implicated in degradation of endocytosed cargo(PubMed:9159129, PubMed:23167963, PubMed:25445562, PubMed:25908847). Required for fusion of autophagosomes with lysosomes(PubMed:25783203). May link the HOPS complex to endosomal Rab7 via its association with RILP and to lysosomal membranes via its association with ARL8B, suggesting that these interactions may bring the compartments to close proximity for fusion(PubMed:25445562, PubMed:25908847). Involved in the direct trans-Golgi network to late endosomes transport of lysosomal membrane proteins independently of HOPS(PubMed:23322049). Involved in sorting to the regulated secretory pathway presumably implicating the AP-3 adaptor complex(By similarity). May play a role in HOPS-independent function in the regulated secretory pathway(PubMed:24210660).
- 分子量
- 70 kDa, 93 kDa
- 基因ID
- 27072
- UniProt
- P49754
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