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Tubulin 抗体 (acLys40)

TUB 适用: 人, 小鼠, 大鼠, 犬 WB, ELISA, IHC, IF 宿主: 小鼠 Monoclonal 6A10 unconjugated
产品编号 ABIN7120355
发货至: 中国
  • 抗原 See all Tubulin (TUB) 抗体
    Tubulin (TUB)
    抗原表位
    • 2
    • 1
    • 1
    acLys40
    适用
    • 7
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠, 犬
    宿主
    • 7
    • 3
    • 1
    小鼠
    克隆类型
    • 7
    • 4
    单克隆
    标记
    • 11
    This Tubulin antibody is un-conjugated
    应用范围
    • 11
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
    纯化方法
    Protein A+G purification
    纯度
    ≥95 % as determined by SDS-PAGE
    免疫原
    tubulin, alpha 1a
    克隆位点
    6A10
    亚型
    IgG1
    Top Product
    Discover our top product TUB Primary Antibody
  • 应用备注
    WB: 1:500-1:5000, IF: 1:20-1:200, IHC: 1:20-1:200
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    有效期
    12 months
  • 抗原
    Tubulin (TUB)
    别名
    tubulin (TUB 产品)
    别名
    4t antibody, B4t antibody, BETA 98B antibody, CG4869 antibody, DTB1 antibody, Dmbeta4 antibody, Dmel\\CG4869 antibody, T antibody, Tub antibody, beta-Tub antibody, beta-Tub97EF antibody, beta-tub antibody, beta4 antibody, beta4t antibody, beta97F antibody, betaTub4 antibody, betaTub98BC antibody, betaTub98C antibody, beta-Tubulin at 97EF antibody, betaTub97EF antibody
    背景
    Synonyms:Acetylated alpha tubulin, Acetylated tubulin, acetylated-a-tubulin, acetyl-a-tubulin, alpha tubulin, Alpha tubulin 3, tubulin,TUBA1A Background:Tubulin, composed of heterodimers of alpha and beta tubulin, is the mainly component of microtubules which play important roles in cell motility, mitosis, and intracellular vesicle transport. Both alpha and beta tubulin undergo several posttranslational modifications such as polyglutamylation and acetylation/deacetylation. Tubulin acetylation occurs on lysine-40 at the N-terminal of alpha tubulin and is conserved across species. The histone deacetylase HDAC6 and SIRT2 has been identified as tubulin deacetylases. Reversible acetylation of alpha tubulin may be implicated in regulating microtubule stability, cell motility, and axon regeneration. The level of acetylated tubulin has been linked to epithelial malignancies and sensitivity to chemotherapy. In addition, acetylated tubulin has been widely used as a marker for primary cilia. This antibody is specific to the acetylated tubulin, it does not recognize non-acetylated tubulin.
    分子量
    52 kDa
    基因ID
    7846
    UniProt
    Q71U36
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