TOP3A 抗体
-
- 抗原 See all TOP3A 抗体
- TOP3A (Topoisomerase (DNA) III alpha (TOP3A))
-
适用
- 人, 小鼠, 大鼠
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This TOP3A antibody is un-conjugated
-
应用范围
- Western Blotting (WB), ELISA, Immunoprecipitation (IP)
- 纯化方法
- Immunogen affinity purified
- 纯度
- ≥95 % as determined by SDS-PAGE
- 免疫原
- topoisomerase(DNA) III alpha
- 亚型
- IgG
- Top Product
- Discover our top product TOP3A Primary Antibody
-
anti-Topoisomerase (DNA) III alpha (TOP3A) (C-Term) antibody
TOP3A 适用: 人, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Topoisomerase (DNA) III alpha (TOP3A) (Internal Region) antibodyTOP3A 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Topoisomerase (DNA) III alpha (TOP3A) antibodyTOP3A 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Topoisomerase (DNA) III alpha (TOP3A) (AA 1-100) antibodyTOP3A 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Topoisomerase (DNA) III alpha (TOP3A) antibodyTOP3A 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
-
- 应用备注
- WB: 1:500-1:2000, IP: 1:200-1:2000
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
- 有效期
- 12 months
-
- 抗原
- TOP3A (Topoisomerase (DNA) III alpha (TOP3A))
- 别名
- TOP3A (TOP3A 产品)
- 别名
- TOP3 antibody, DNA topoisomerase III alpha antibody, topoisomerase (DNA) III alpha antibody, Top3a antibody, TOP3A antibody
- 背景
- Synonyms:TOP3 Background:Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone. Essential component of the RMI complex, a complex that plays an important role in the processing of homologous recombination intermediates to limit DNA crossover formation in cells. Has DNA decatenation activity.
- 分子量
- 100-110 kDa
- 基因ID
- 7156
- UniProt
- Q13472
- 途径
- DNA Damage Repair
-
