TAF1C antibody, Tafi95 antibody, mTAFI95 antibody, MGC:39976 antibody, SL1 antibody, TAFI110 antibody, TAFI95 antibody, TATA-box binding protein associated factor, RNA polymerase I subunit C antibody, TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa antibody, TATA-box binding protein associated factor, RNA polymerase I, C antibody, TATA-box binding protein associated factor, RNA polymerase 1 subunit C antibody, TAF1C antibody, Taf1c antibody
背景
Synonyms: Background:Initiation of transcription by RNA polymerase I requires the formation of a complex composed of the TATA-binding protein (TBP) and three TBP-associated factors (TAFs) specific for RNA polymerase I. This complex, known as SL1, binds to the core promoter of ribosomal RNA genes to position the polymerase properly and acts as a channel for regulatory signals. This gene encodes the largest SL1-specific TAF. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.