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SNX27 抗体

SNX27 适用: 人, 小鼠, 大鼠 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7119360
发货至: 中国
  • 抗原 See all SNX27 抗体
    SNX27 (Sorting Nexin 27 (SNX27))
    适用
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    人, 小鼠, 大鼠
    宿主
    • 45
    • 1
    克隆类型
    • 45
    • 1
    多克隆
    标记
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    This SNX27 antibody is un-conjugated
    应用范围
    • 21
    • 18
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    • 5
    • 3
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    ELISA, Western Blotting (WB), Immunohistochemistry (IHC)
    纯化方法
    Immunogen affinity purified
    纯度
    ≥95 % as determined by SDS-PAGE
    免疫原
    sorting nexin family member 27
    亚型
    IgG
    Top Product
    Discover our top product SNX27 Primary Antibody
  • 应用备注
    WB: 1:500-1:2000, IHC: 1:20-1:200
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    有效期
    12 months
  • 抗原
    SNX27 (Sorting Nexin 27 (SNX27))
    别名
    SNX27 (SNX27 产品)
    别名
    MRT1 antibody, MY014 antibody, 5730552M22Rik antibody, ESTM45 antibody, ESTM47 antibody, R75405 antibody, mKIAA0488 antibody, Mrt1 antibody, sorting nexin family member 27 antibody, SNX27 antibody, Snx27 antibody
    背景
    Synonyms:KIAA0488 Background:Involved in the retrograde transport from endosome to plasma membrane, a trafficking pathway that promotes the recycling of internalized transmembrane proteins. Following internalization, endocytosed transmembrane proteins are delivered to early endosomes and recycled to the plasma membrane instead of being degraded in lysosomes. SNX27 specifically binds and directs sorting of a subset of transmembrane proteins containing a PDZ-binding motif at the C-terminus: following interaction with target transmembrane proteins, associates with the retromer complex, preventing entry into the lysosomal pathway, and promotes retromer-tubule based plasma membrane recycling. SNX27 also binds with the WASH complex. Interacts with membranes containing phosphatidylinositol-3-phosphate(PtdIns(3P)). May participate in establishment of natural killer cell polarity. Recruits CYTIP to early endosomes.
    分子量
    52-60 kDa
    基因ID
    81609
    UniProt
    Q96L92
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