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SNAPIN 抗体

SNAPIN 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IP, IF, FACS 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7119201
发货至: 中国
  • 抗原 See all SNAPIN 抗体
    SNAPIN (SNAP-Associated Protein (SNAPIN))
    适用
    • 34
    • 3
    • 3
    • 1
    人, 小鼠, 大鼠
    宿主
    • 26
    • 8
    • 1
    克隆类型
    • 30
    • 5
    多克隆
    标记
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    This SNAPIN antibody is un-conjugated
    应用范围
    • 13
    • 13
    • 13
    • 9
    • 8
    • 5
    • 4
    • 4
    • 4
    • 3
    • 2
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    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP), Immunofluorescence (IF), Flow Cytometry (FACS)
    纯化方法
    Immunogen affinity purified
    纯度
    ≥95 % as determined by SDS-PAGE
    免疫原
    SNAP-associated protein
    亚型
    IgG
    Top Product
    Discover our top product SNAPIN Primary Antibody
  • 应用备注
    WB: 1:500-1:2000, IP: 1:200-1:2000, IHC: 1:20-1:200, IF: 1:20-1:200
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    有效期
    12 months
  • 抗原
    SNAPIN (SNAP-Associated Protein (SNAPIN))
    别名
    SNAPIN (SNAPIN 产品)
    别名
    SNAPAP antibody, si:dkey-222b8.2 antibody, SNAPIN antibody, BLOC1S7 antibody, BLOS7 antibody, 25kDa antibody, AA407989 antibody, AV026596 antibody, Bloc1s7 antibody, Snap25bp antibody, Snapap antibody, SNAP associated protein antibody, SNAP-associated protein L homeolog antibody, SNAP-associated protein antibody, SNAPIN antibody, snapin.L antibody, snapin antibody, Snapin antibody
    背景
    Synonyms:BLOC1S7, SNAP25BP, SNAPAP Background:Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles(LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Plays a role in intracellular vesicle trafficking and synaptic vesicle recycling. May modulate a step between vesicle priming, fusion and calcium-dependent neurotransmitter release through its ability to potentiate the interaction of synaptotagmin with the SNAREs and the plasma-membrane-associated protein SNAP25. Its phosphorylation state influences exocytotic protein interactions and may regulate synaptic vesicle exocytosis. May also have a role in the mechanisms of SNARE-mediated membrane fusion in non-neuronal cells(PubMed:17182842, PubMed:18167355). As part of the BORC complex may play a role in lysosomes movement and localization at the cell periphery. Associated with the cytosolic face of lysosomes, the BORC complex may recruit ARL8B and couple lysosomes to microtubule plus-end-directed kinesin motor(PubMed:25898167).
    分子量
    15-18 kDa
    基因ID
    23557
    UniProt
    O95295
    途径
    Synaptic Membrane, Synaptic Vesicle Exocytosis
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