SRRM1 抗体
Quick Overview for SRRM1 抗体 (ABIN7118908)
抗原
See all SRRM1 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- SRRM1 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- serine/arginine repetitive matrix 1
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亚型
- IgG
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应用备注
- WB: 1:500-1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- SRRM1 (Serine/arginine Repetitive Matrix 1 (SRRM1))
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别名
- SRRM1
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背景
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Synonyms: Serine/arginine repetitive matrix protein 1|SR-related nuclear matrix protein of 160 kDa (SRm160)|Ser/Arg-related nuclear matrix protein|SRRM1|SRM160
Background: Part of pre-and post-splicing multiprotein mRNP complexes. Involved in numerous pre-mRNA processing events. Promotes constitutive and exonic splicing enhancer(ESE)-dependent splicing activation by bridging together sequence-specific(SR family proteins, SFRS4, SFRS5 and TRA2B/SFRS10) and basal snRNP(SNRP70 and SNRPA1) factors of the spliceosome. Stimulates mRNA 3'-end cleavage independently of the formation of an exon junction complex. Binds both pre-mRNA and spliced mRNA 20-25 nt upstream of exon-exon junctions. Binds RNA and DNA with low sequence specificity and has similar preference for either double-or single-stranded nucleic acid substrates.
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分子量
- 120-160 kDa
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基因ID
- 10250
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UniProt
- Q8IYB3
抗原
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