Synonyms:D3S1231E, SEC13L1, SEC13R Background:Functions as a component of the nuclear pore complex(NPC) and the COPII coat. At the endoplasmic reticulum, SEC13 is involved in the biogenesis of COPII-coated vesicles. As a component of the GATOR subcomplex GATOR2, functions as an activator of the amino acid-sensing branch of the TORC1 pathway. Inhibits the GATOR1 subcomplex, an inhibitor of the amino acid-sensing branch of the TORC1 pathway(PubMed:23723238). Functions downstream and is regulated by amino acid sensors like SESN2(Probable).