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RBM25 抗体

RBM25 适用: 小鼠, 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7118681
发货至: 中国
  • 抗原 See all RBM25 抗体
    RBM25 (RNA Binding Motif Protein 25 (RBM25))
    适用
    • 21
    • 8
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    • 2
    • 1
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    小鼠, 人
    宿主
    • 23
    克隆类型
    • 23
    多克隆
    标记
    • 9
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    • 1
    • 1
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    This RBM25 antibody is un-conjugated
    应用范围
    • 13
    • 13
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    纯化方法
    Immunogen affinity purified
    纯度
    ≥95 % as determined by SDS-PAGE
    免疫原
    RNA binding motif protein 25
    亚型
    IgG
    Top Product
    Discover our top product RBM25 Primary Antibody
  • 应用备注
    WB: 1:200-1:2000, IP: 1:200-1:2000, IHC: 1:20-1:200
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    有效期
    12 months
  • 抗原
    RBM25 (RNA Binding Motif Protein 25 (RBM25))
    别名
    RBM25 (RBM25 产品)
    别名
    fi03e10 antibody, zgc:56208 antibody, wu:fi03e10 antibody, si:ch211-105d18.5 antibody, rnpc7 antibody, s164 antibody, NET52 antibody, RED120 antibody, RNPC7 antibody, S164 antibody, Snu71 antibody, fSAP94 antibody, 2600011C06Rik antibody, 2610015J01Rik antibody, A130095G20Rik antibody, AI159652 antibody, AL023075 antibody, AU043498 antibody, RNA binding motif protein 25b antibody, RNA binding motif protein 25 antibody, RNA binding motif protein 25 S homeolog antibody, putative rna binding motif protein 25 antibody, rbm25b antibody, Rbm25 antibody, rbm25.S antibody, rbm25 antibody, RBM25 antibody, Smp_078610 antibody
    背景
    Synonyms:fSAP94, NET52, Protein S164, RBM25, RED120, RNA binding motif protein 25, RNA binding protein 25, RNPC7, S164 Background:RNA-binding protein that acts as a regulator of alternative pre-mRNA splicing. Involved in apoptotic cell death through the regulation of the apoptotic factor BCL2L1 isoform expression. Modulates the ratio of proapoptotic BCL2L1 isoform S to antiapoptotic BCL2L1 isoform L mRNA expression. When overexpressed, stimulates proapoptotic BCL2L1 isoform S 5'-splice site(5'-ss) selection, whereas its depletion caused the accumulation of antiapoptotic BCL2L1 isoform L. Promotes BCL2L1 isoform S 5'-ss usage through the 5'-CGGGCA-3' RNA sequence. Its association with LUC7L3 promotes U1 snRNP binding to a weak 5' ss in a 5'-CGGGCA-3'-dependent manner. Binds to the exonic splicing enhancer 5'-CGGGCA-3' RNA sequence located within exon 2 of the BCL2L1 pre-mRNA. Also involved in the generation of an abnormal and truncated splice form of SCN5A in heart failure.
    分子量
    110-120 kDa
    基因ID
    58517
    UniProt
    P49756
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