RBM25 抗体
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- 抗原 See all RBM25 抗体
- RBM25 (RNA Binding Motif Protein 25 (RBM25))
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适用
- 小鼠, 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This RBM25 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- 纯化方法
- Immunogen affinity purified
- 纯度
- ≥95 % as determined by SDS-PAGE
- 免疫原
- RNA binding motif protein 25
- 亚型
- IgG
- Top Product
- Discover our top product RBM25 Primary Antibody
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anti-RNA Binding Motif Protein 25 (RBM25) (AA 614-843) antibody
RBM25 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-RNA Binding Motif Protein 25 (RBM25) antibodyRBM25 适用: 小鼠, 人 IF 宿主: 兔 Polyclonal unconjugated
anti-RNA Binding Motif Protein 25 (RBM25) (AA 285-334) antibodyRBM25 适用: 小鼠, 人, 大鼠, Cow, 犬, 豚鼠, 马, 兔, 斑马鱼, 小鸡, 猴, Pig, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB: 1:200-1:2000, IP: 1:200-1:2000, IHC: 1:20-1:200
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
- 有效期
- 12 months
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- 抗原
- RBM25 (RNA Binding Motif Protein 25 (RBM25))
- 别名
- RBM25 (RBM25 产品)
- 背景
- Synonyms:fSAP94, NET52, Protein S164, RBM25, RED120, RNA binding motif protein 25, RNA binding protein 25, RNPC7, S164 Background:RNA-binding protein that acts as a regulator of alternative pre-mRNA splicing. Involved in apoptotic cell death through the regulation of the apoptotic factor BCL2L1 isoform expression. Modulates the ratio of proapoptotic BCL2L1 isoform S to antiapoptotic BCL2L1 isoform L mRNA expression. When overexpressed, stimulates proapoptotic BCL2L1 isoform S 5'-splice site(5'-ss) selection, whereas its depletion caused the accumulation of antiapoptotic BCL2L1 isoform L. Promotes BCL2L1 isoform S 5'-ss usage through the 5'-CGGGCA-3' RNA sequence. Its association with LUC7L3 promotes U1 snRNP binding to a weak 5' ss in a 5'-CGGGCA-3'-dependent manner. Binds to the exonic splicing enhancer 5'-CGGGCA-3' RNA sequence located within exon 2 of the BCL2L1 pre-mRNA. Also involved in the generation of an abnormal and truncated splice form of SCN5A in heart failure.
- 分子量
- 110-120 kDa
- 基因ID
- 58517
- UniProt
- P49756
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