RRP8 抗体
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- 抗原 See all RRP8 抗体
- RRP8 (Ribosomal RNA Processing 8 (RRP8))
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适用
- 人, 大鼠, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This RRP8 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
- 纯化方法
- Immunogen affinity purified
- 纯度
- ≥95 % as determined by SDS-PAGE
- 免疫原
- ribosomal RNA processing 8, methyltransferase, homolog(yeast)
- 亚型
- IgG
- Top Product
- Discover our top product RRP8 Primary Antibody
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anti-Ribosomal RNA Processing 8 (RRP8) antibody
RRP8 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ribosomal RNA Processing 8 (RRP8) (Internal Region) antibodyRRP8 适用: 人 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Ribosomal RNA Processing 8 (RRP8) (AA 1-456) antibodyRRP8 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Ribosomal RNA Processing 8 (RRP8) (AA 271-320) antibodyRRP8 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Ribosomal RNA Processing 8 (RRP8) (AA 100-149) antibodyRRP8 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Ribosomal RNA Processing 8 (RRP8) (AA 89-138) antibodyRRP8 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Ribosomal RNA Processing 8 (RRP8) (N-Term) antibodyRRP8 适用: 人, 大鼠, Cow, 马, 兔 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB: 1:500-1:2000, IHC: 1:20-1:200, IF: 1:20-1:200
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
- 有效期
- 12 months
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- 抗原
- RRP8 (Ribosomal RNA Processing 8 (RRP8))
- 别名
- RRP8 (RRP8 产品)
- 别名
- KIAA0409 antibody, 1500003O22Rik antibody, 2900001K19Rik antibody, AW538116 antibody, RGD1308302 antibody, ribosomal RNA processing 8 antibody, ribosomal RNA processing 8, methyltransferase, homolog (yeast) antibody, RRP8 antibody, Rrp8 antibody
- 背景
- Synonyms:KIAA0409, NML Background:Essential component of the eNoSC(energy-dependent nucleolar silencing) complex, a complex that mediates silencing of rDNA in response to intracellular energy status and acts by recruiting histone-modifying enzymes. The eNoSC complex is able to sense the energy status of cell: upon glucose starvation, elevation of NAD(+)/NADP(+) ratio activates SIRT1, leading to histone H3 deacetylation followed by dimethylation of H3 at 'Lys-9'(H3K9me2) by SUV39H1 and the formation of silent chromatin in the rDNA locus. In the complex, RRP8 binds to H3K9me2 and probably acts as a methyltransferase. Its substrates are however unknown.
- 分子量
- 51 kDa
- 基因ID
- 23378
- UniProt
- O43159
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