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RHBDD1 抗体

RHBDD1 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7118505
发货至: 中国
  • 抗原 See all RHBDD1 抗体
    RHBDD1 (Rhomboid Domain Containing 1 (RHBDD1))
    适用
    • 6
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 6
    克隆类型
    • 6
    多克隆
    标记
    • 6
    This RHBDD1 antibody is un-conjugated
    应用范围
    • 5
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA
    纯化方法
    Immunogen affinity purified
    纯度
    ≥95 % as determined by SDS-PAGE
    免疫原
    rhomboid domain containing 1
    亚型
    IgG
    Top Product
    Discover our top product RHBDD1 Primary Antibody
  • 应用备注
    WB: 1:500-1:2000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    有效期
    12 months
  • 抗原
    RHBDD1 (Rhomboid Domain Containing 1 (RHBDD1))
    别名
    RHBDD1 (RHBDD1 产品)
    别名
    MGC84665 antibody, RRP4 antibody, 4930418P06Rik antibody, mRHBDD1 antibody, RGD1306477 antibody, rRHBDD1 antibody, rhomboid domain containing 1 antibody, rhomboid domain containing 1 L homeolog antibody, RHBDD1 antibody, rhbdd1.L antibody, rhbdd1 antibody, Rhbdd1 antibody
    背景
    Synonyms:RHBDL4 Background:Intramembrane-cleaving serine protease that cleaves single transmembrane or multi-pass membrane proteins in the hydrophobic plane of the membrane, luminal loops and juxtamembrane regions. Involved in regulated intramembrane proteolysis and the subsequent release of functional polypeptides from their membrane anchors. Functional component of endoplasmic reticulum-associated degradation(ERAD) for misfolded membrane proteins. Required for the degradation process of some specific misfolded endoplasmic reticulum(ER) luminal proteins. Participates in the transfer of misfolded proteins from the ER to the cytosol, where they are destroyed by the proteasome in a ubiquitin-dependent manner. Functions in BIK, MPZ, PKD1, PTCRA, RHO, STEAP3 and TRAC processing. Involved in the regulation of exosomal secretion, inhibits the TSAP6-mediated secretion pathway. Involved in the regulation of apoptosis, modulates BIK-mediated apoptotic activity. Also plays a role in the regulation of spermatogenesis, inhibits apoptotic activity in spermatogonia.
    分子量
    36 kDa
    基因ID
    84236
    UniProt
    Q8TEB9
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