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ARHGEF4 抗体
ARHGEF4
适用: 人, 小鼠
WB, ELISA, IHC
宿主: 兔
Polyclonal
unconjugated
ARHGEF4抗体详情
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抗原
See all ARHGEF4 抗体
ARHGEF4
(rho Guanine Nucleotide Exchange Factor (GEF) 4 (ARHGEF4))
适用
All reactivities for ARHGEF4 抗体
人, 小鼠
宿主
All hosts for ARHGEF4 抗体
兔
克隆类型
All clonalities for ARHGEF4 抗体
多克隆
标记
All conjugates for ARHGEF4 抗体
This ARHGEF4 antibody is un-conjugated
应用范围
Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
纯化方法
Immunogen affinity purified
纯度
≥95 % as determined by SDS-PAGE
免疫原
Rho guanine nucleotide exchange factor(GEF) 4
亚型
IgG
Top Product
Discover our top product ARHGEF4 Primary Antibody
Alternatives
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使用细节
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应用备注
WB: 1:500-1:2000, IHC: 1:20-1:200
限制
仅限研究用
贮存及处理
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状态
Liquid
缓冲液
PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
-20 °C
储存方法
-20°C for 12 months (Avoid repeated freeze / thaw cycles.)
有效期
12 months
ARHGEF4目标详情
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抗原
ARHGEF4
(rho Guanine Nucleotide Exchange Factor (GEF) 4 (ARHGEF4))
别名
ARHGEF4 (ARHGEF4 产品 )
别名
ARHGEF4 antibody, ASEF antibody, ASEF1 antibody, GEF4 antibody, STM6 antibody, 9330140K16Rik antibody, Asef antibody, ENSMUSG00000070955 antibody, Rho guanine nucleotide exchange factor 4 antibody, uncharacterized LOC100470646 antibody, rho guanine nucleotide exchange factor 4 antibody, Rho guanine nucleotide exchange factor (GEF) 4 antibody, ARHGEF4 antibody, arhg4 antibody, LOC100470646 antibody, LOC100544917 antibody, Arhgef4 antibody
背景
Synonyms:KIAA1112 Background:Acts as guanine nucleotide exchange factor(GEF) for RHOA, RAC1 and CDC42 GTPases. Binding of APC may activate RAC1 GEF activity. The APC-ARHGEF4 complex seems to be involved in cell migration as well as in E-cadherin-mediated cell-cell adhesion. Required for MMP9 up-regulation via the JNK signaling pathway in colorectal tumor cells. Involved in tumor angiogenesis and may play a role in intestinal adenoma formation and tumor progression.
分子量
72 kDa
基因ID
50649
UniProt
Q9NR80
途径
Neurotrophin Signaling Pathway
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