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RAB7B 抗体

RAB7B 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7118233
发货至: 中国
  • 抗原 See all RAB7B 抗体
    RAB7B (RAB7B, Member RAS Oncogene Family (RAB7B))
    适用
    • 27
    • 1
    • 1
    人, 小鼠
    宿主
    • 21
    • 6
    克隆类型
    • 24
    • 3
    多克隆
    标记
    • 14
    • 3
    • 3
    • 3
    • 2
    • 2
    This RAB7B antibody is un-conjugated
    应用范围
    • 23
    • 22
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA
    纯化方法
    Immunogen affinity purified
    纯度
    ≥95 % as determined by SDS-PAGE
    免疫原
    RAB7B, member RAS oncogene family
    亚型
    IgG
    Top Product
    Discover our top product RAB7B Primary Antibody
  • 应用备注
    WB: 1:500-1:2000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    有效期
    12 months
  • 抗原
    RAB7B (RAB7B, Member RAS Oncogene Family (RAB7B))
    别名
    RAB7B (RAB7B 产品)
    别名
    RGD1562617 antibody, RAB7B antibody, RAB7 antibody, Rab7b antibody, Rab7b, member RAS oncogene family antibody, rab7B protein antibody, RAB7B, member RAS oncogene family antibody, RAB7B, member RAS oncogene family S homeolog antibody, Rab7b antibody, rab7B antibody, RAB7B antibody, rab7b.S antibody, rab7b antibody
    背景
    Synonyms:Ras-related protein Rab-7b, RAB7B Background:Controls vesicular trafficking from endosomes to the trans-Golgi network(TGN). Acts as a negative regulator of TLR9 signaling and can suppress TLR9-triggered TNFA, IL6, and IFNB production in macrophages by promoting TLR9 lysosomal degradation. Also negatively regulates TLR4 signaling in macrophages by promoting lysosomal degradation of TLR4. Promotes megakaryocytic differentiation by increasing NF-kappa-B-dependent IL6 production and subsequently enhancing the association of STAT3 with GATA1. Not involved in the regulation of the EGF-and EGFR degradation pathway.
    分子量
    23 kDa
    基因ID
    338382
    UniProt
    Q96AH8
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