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RAB10 抗体

RAB10 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7118183
发货至: 中国
  • 抗原 See all RAB10 抗体
    RAB10 (RAB10, Member RAS Oncogene Family (RAB10))
    适用
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    人, 小鼠, 大鼠
    宿主
    • 36
    • 2
    • 1
    克隆类型
    • 37
    • 2
    多克隆
    标记
    • 16
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    This RAB10 antibody is un-conjugated
    应用范围
    • 28
    • 22
    • 13
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    纯化方法
    Immunogen affinity purified
    纯度
    ≥95 % as determined by SDS-PAGE
    免疫原
    RAB10, member RAS oncogene family
    亚型
    IgG
    Top Product
    Discover our top product RAB10 Primary Antibody
  • 应用备注
    WB: 1:500-1:2000, IHC: 1:20-1:200
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    有效期
    12 months
  • 抗原
    RAB10 (RAB10, Member RAS Oncogene Family (RAB10))
    别名
    RAB10 (RAB10 产品)
    别名
    AW107754 antibody, Ac1075 antibody, zgc:92757 antibody, rab10 antibody, RAB10, member RAS oncogene family antibody, RAB10, member RAS oncogene family L homeolog antibody, RAB10 antibody, Rab10 antibody, rab10 antibody, rab10.L antibody
    背景
    Synonyms: Background:The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion(By similarity). That Rab is mainly involved in the biosynthetic transport of proteins from the Golgi to the plasma membrane. Regulates, for instance, SLC2A4/GLUT4 glucose transporter-enriched vesicles delivery to the plasma membrane. In parallel, it regulates the transport of TLR4, a toll-like receptor to the plasma membrane and therefore may be important for innate immune response. Plays also a specific role in asymmetric protein transport to the plasma membrane within the polarized neuron and epithelial cells. In neurons, it is involved in axonogenesis through regulation of vesicular membrane trafficking toward the axonal plasma membrane while in epithelial cells, it regulates transport from the Golgi to the basolateral membrane. Moreover, may play a role in the basolateral recycling pathway and in phagosome maturation. According to PubMed:23263280, may play a role in endoplasmic reticulum dynamics and morphology controlling tubulation along microtubules and tubules fusion.
    分子量
    23 kDa
    基因ID
    10890
    UniProt
    P61026
    途径
    Asymmetric Protein Localization, SARS-CoV-2 Protein Interactome
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