MGC84055 antibody, sdpii antibody, pacsin1 antibody, x-PACSIN2 antibody, fe25d06 antibody, wu:fe25d06 antibody, zgc:114042 antibody, PACSIN1 antibody, SDPI antibody, A830061D09Rik antibody, H74 antibody, mKIAA1379 antibody, syndapin antibody, protein kinase C and casein kinase substrate in neurons 1 antibody, protein kinase C and casein kinase substrate in neurons 1 S homeolog antibody, protein kinase C and casein kinase substrate in neurons 2 antibody, protein kinase C and casein kinase substrate in neurons 1b antibody, PACSIN1 antibody, pacsin1.S antibody, pacsin2 antibody, pacsin1b antibody, Pacsin1 antibody
背景
Synonyms:KIAA1379 Background:Plays a role in the reorganization of the microtubule cytoskeleton via its interaction with MAPT, this decreases microtubule stability and inhibits MAPT-induced microtubule polymerization. Plays a role in cellular transport processes by recruiting DNM1, DNM2 and DNM3 to membranes. Plays a role in the reorganization of the actin cytoskeleton and in neuron morphogenesis via its interaction with COBL and WASL, and by recruiting COBL to the cell cortex. Plays a role in the regulation of neurite formation, neurite branching and the regulation of neurite length. Required for normal synaptic vesicle endocytosis, this process retrieves previously released neurotransmitters to accommodate multiple cycles of neurotransmission. Required for normal excitatory and inhibitory synaptic transmission(By similarity). Binds to membranes via its F-BAR domain and mediates membrane tubulation.