电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

PSTPIP1 抗体

PSTPIP1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7117827
发货至: 中国
  • 抗原 See all PSTPIP1 抗体
    PSTPIP1 (Proline-serine-threonine Phosphatase Interacting Protein 1 (PSTPIP1))
    适用
    • 24
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 22
    • 2
    克隆类型
    • 22
    • 2
    多克隆
    标记
    • 14
    • 2
    • 2
    • 2
    • 2
    • 2
    This PSTPIP1 antibody is un-conjugated
    应用范围
    • 24
    • 17
    • 13
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    纯化方法
    Immunogen affinity purified
    纯度
    ≥95 % as determined by SDS-PAGE
    免疫原
    proline-serine-threonine phosphatase interacting protein 1
    亚型
    IgG
    Top Product
    Discover our top product PSTPIP1 Primary Antibody
  • 应用备注
    WB: 1:500 - 1:2000, IHC: 1:50 - 1:200
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3 ,
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    有效期
    12 months
  • 抗原
    PSTPIP1 (Proline-serine-threonine Phosphatase Interacting Protein 1 (PSTPIP1))
    别名
    PSTPIP1 (PSTPIP1 产品)
    别名
    cd2bp1 antibody, cd2bp1l antibody, cd2bp1s antibody, h-pip antibody, papas antibody, pstpip antibody, PSTPIP1 antibody, CD2BP1 antibody, CD2BP1L antibody, CD2BP1S antibody, H-PIP antibody, PAPAS antibody, PSTPIP antibody, def-2 antibody, proline-serine-threonine phosphatase interacting protein 1 antibody, proline-serine-threonine phosphatase interacting protein 1 S homeolog antibody, proline-serine-threonine phosphatase-interacting protein 1 antibody, PSTPIP1 antibody, pstpip1.S antibody, pstpip1 antibody, Pstpip1 antibody
    背景
    Synonyms:CD2BP1 Background:This gene encodes a cytoskeletal protein that is highly expressed in hemopoietic tissues. This protein functions via its interaction with several different proteins involved in cytoskeletal organization and inflammatory processes. It binds to the cytoplasmic tail of CD2, an effector of T cell activation and adhesion, downregulating CD2-triggered adhesion. It binds PEST-type protein tyrosine phosphatases (PTP) and directs them to c-Abl kinase to mediate c-Abl dephosphorylation, thereby, regulating c-Abl activity. It also interacts with pyrin, which is found in association with the cytoskeleton in myeloid/monocytic cells and modulates immunoregulatory functions. Mutations in this gene are associated with PAPA (pyogenic sterile arthritis, pyoderma gangrenosum, and acne) syndrome. It is hypothesized that the disease-causing mutations compromise physiologic signaling necessary for the maintenance of a proper inflammatory response.
    分子量
    48 kDa
    基因ID
    9051
    UniProt
    O43586
You are here:
客服