PRICKLE1 抗体
Quick Overview for PRICKLE1 抗体 (ABIN7117768)
抗原
See all PRICKLE1 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- PRICKLE1 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- prickle homolog 1(Drosophila)
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亚型
- IgG
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应用备注
- WB: 1:500-1:2000, IP: 1:200-1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- PRICKLE1 (Prickle-Like Protein 1 (PRICKLE1))
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别名
- PRICKLE1
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背景
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Synonyms: Prickle-like protein 1|REST/NRSF-interacting LIM domain protein 1|PRICKLE1|RILP
Background: Involved in the planar cell polarity pathway that controls convergent extension during gastrulation and neural tube closure. Convergent extension is a complex morphogenetic process during which cells elongate, move mediolaterally, and intercalate between neighboring cells, leading to convergence toward the mediolateral axis and extension along the anteroposterior axis. Necessary for nuclear localization of REST. May serve as nuclear receptor.
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分子量
- 94 kDa, 55-60 kDa
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基因ID
- 144165
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UniProt
- Q96MT3
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途径
- WNT signaling, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development, Protein targeting to Nucleus
抗原
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