fb53g01 antibody, zgc:91954 antibody, wu:fb53g01 antibody, poly(A) binding protein interacting protein 1 antibody, polyadenylate binding protein-interacting protein 1 antibody, poly(A) binding protein interacting protein 1 S homeolog antibody, PAIP1 antibody, paip1 antibody, Paip1 antibody, paip1.S antibody
背景
Synonyms: Background:Acts as a coactivator in the regulation of translation initiation of poly(A)-containing mRNAs. Its stimulatory activity on translation is mediated via its action on PABPC1. Competes with PAIP2 for binding to PABPC1. Its association with EIF4A and PABPC1 may potentiate contacts between mRNA termini. May also be involved in translationally coupled mRNA turnover. Implicated with other RNA-binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of instability(mCRD) domain.