PAIP2A antibody, DKFZp469O1314 antibody, 2310050K10Rik antibody, AU045972 antibody, paip2 antibody, poly(A) binding protein interacting protein 2 antibody, polyadenylate-binding protein-interacting protein 2 antibody, poly(A) binding protein interacting protein 2B L homeolog antibody, PAIP2 antibody, Paip2 antibody, paip2b.L antibody
背景
Synonyms:PAIP2A Background:Acts as a repressor in the regulation of translation initiation of poly(A)-containing mRNAs. Its inhibitory activity on translation is mediated via its action on PABPC1. Displaces the interaction of PABPC1 with poly(A) RNA and competes with PAIP1 for binding to PABPC1. Its association with PABPC1 results in disruption of the cytoplasmic poly(A) RNP structure organization.