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PIWIL1 抗体

PIWIL1 适用: 人, 小鼠 WB, IHC, ELISA, IF, IP 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7117540
发货至: 中国
  • 抗原 See all PIWIL1 抗体
    PIWIL1 (Piwi-Like 1 (PIWIL1))
    适用
    • 42
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    • 1
    人, 小鼠
    宿主
    • 44
    • 4
    • 1
    • 1
    克隆类型
    • 40
    • 10
    多克隆
    标记
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    This PIWIL1 antibody is un-conjugated
    应用范围
    • 25
    • 13
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    • 7
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    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP)
    纯化方法
    Immunogen affinity purified
    纯度
    ≥95 % as determined by SDS-PAGE
    免疫原
    piwi-like 1(Drosophila)
    亚型
    IgG
    Top Product
    Discover our top product PIWIL1 Primary Antibody
  • 应用备注
    WB: 1:500-1:2000, IP: 1:200-1:1000, IHC: 1:20-1:200, IF: 1:20-1:200
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    有效期
    12 months
  • 抗原
    PIWIL1 (Piwi-Like 1 (PIWIL1))
    别名
    PIWIL1 (PIWIL1 产品)
    别名
    ziwi antibody, PIWI antibody, HIWI antibody, MIWI antibody, piwi like RNA-mediated gene silencing 1 antibody, PIWI-like protein 1 antibody, putative PIWI-like protein 1 antibody, putative argonaut-like protein antibody, piwi-like RNA-mediated gene silencing 1 antibody, PIWIL1 antibody, Tb10.70.5520 antibody, LINJ_21_0470 antibody, LBRM_21_0470 antibody, piwil1 antibody, Piwil1 antibody
    背景
    Synonyms:HIWI Background:Plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Directly binds methylated piRNAs, a class of 24 to 30 nucleotide RNAs that are generated by a Dicer-independent mechanism and are primarily derived from transposons and other repeated sequence elements. Besides their function in transposable elements repression, piRNAs are probably involved in other processes during meiosis such as translation regulation. Probable component of some RISC complex, which mediates RNA cleavage and translational silencing. Also plays a role in the formation of chromatoid bodies and is required for some miRNAs stability(By similarity). Isoform 3 may be a negative developmental regulator(PubMed:12037681, PubMed:16287078).
    分子量
    85-95 kDa
    基因ID
    9271
    UniProt
    Q96J94
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