PHAX 抗体
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- 抗原 See all PHAX 抗体
- PHAX (phosphorylated Adaptor For RNA Export (PHAX))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PHAX antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 纯化方法
- Immunogen affinity purified
- 纯度
- ≥95 % as determined by SDS-PAGE
- 免疫原
- phosphorylated adaptor for RNA export
- 亚型
- IgG
- Top Product
- Discover our top product PHAX Primary Antibody
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anti-phosphorylated Adaptor For RNA Export (PHAX) (AA 6-243) antibody
PHAX 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-phosphorylated Adaptor For RNA Export (PHAX) (AA 297-326), (C-Term) antibodyPHAX 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB32550 unconjugated
anti-phosphorylated Adaptor For RNA Export (PHAX) (AA 304-334), (C-Term) antibodyPHAX 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB: 1:500-1:2000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
- 有效期
- 12 months
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- 抗原
- PHAX (phosphorylated Adaptor For RNA Export (PHAX))
- 别名
- PHAX (PHAX 产品)
- 背景
- Synonyms:RNUXA Background:A phosphoprotein adapter involved in the XPO1-mediated U snRNA export from the nucleus. Bridge components required for U snRNA export, the cap binding complex(CBC)-bound snRNA on the one hand and the GTPase Ran in its active GTP-bound form together with the export receptor XPO1 on the other. Its phosphorylation in the nucleus is required for U snRNA export complex assembly and export, while its dephosphorylation in the cytoplasm causes export complex disassembly. It is recycled back to the nucleus via the importin alpha/beta heterodimeric import receptor. The directionality of nuclear export is thought to be conferred by an asymmetric distribution of the GTP-and GDP-bound forms of Ran between the cytoplasm and nucleus. Its compartmentalized phosphorylation cycle may also contribute to the directionality of export. Binds strongly to m7G-capped U1 and U5 small nuclear RNAs(snRNAs) in a sequence-unspecific manner and phosphorylation-independent manner(By similarity). Plays also a role in the biogenesis of U3 small nucleolar RNA(snoRNA). Involved in the U3 snoRNA transport from nucleoplasm to Cajal bodies. Binds strongly to m7G-capped U3, U8 and U13 precursor snoRNAs and weakly to trimethylated(TMG)-capped U3, U8 and U13 snoRNAs. Binds also to telomerase RNA.
- 分子量
- 55 kDa
- 基因ID
- 51808
- UniProt
- Q9H814
- 途径
- Ribonucleoprotein Complex Subunit Organization
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