PDE12 抗体
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- 抗原 See all PDE12 抗体
- PDE12 (Phosphodiesterase 12 (PDE12))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PDE12 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunofluorescence (IF)
- 纯化方法
- Immunogen affinity purified
- 纯度
- ≥95 % as determined by SDS-PAGE
- 免疫原
- phosphodiesterase 12
- 亚型
- IgG
- Top Product
- Discover our top product PDE12 Primary Antibody
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- 应用备注
- WB: 1:500-1:2000, IF: 1:20-1:200
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
- 有效期
- 12 months
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- 抗原
- PDE12 (Phosphodiesterase 12 (PDE12))
- 别名
- PDE12 (PDE12 产品)
- 别名
- 2'-PDE antibody, E430028B21Rik antibody, LRRGT00074 antibody, RGD1310975 antibody, phosphodiesterase 12 S homeolog antibody, phosphodiesterase 12 antibody, pde12.S antibody, PDE12 antibody, pde12 antibody, Pde12 antibody
- 背景
- Synonyms: Background:Enzyme that cleaves 2',5'-phosphodiester bond linking adenosines of the 5'-triphosphorylated oligoadenylates, triphosphorylated oligoadenylates referred as 2-5A modulates the 2-5A system. This enzyme degraded triphosphorylated 2-5A to produce AMP and ATP. Also cleaves 3',5'-phosphodiester bond of oligoadenylates. Plays a role as a negative regulator of the The 2-5A system that is one of the major pathways for antiviral and antitumor functions induced by interferons(IFNs). Suppression of this enzyme induces reduction of viral replication in Hela cells, thus counteracting the antiviral pathway probably by inhibiting the 2-5A system.
- 分子量
- 65kd
- 基因ID
- 201626
- UniProt
- Q6L8Q7
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