PHF2 抗体
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- 抗原 See all PHF2 抗体
- PHF2 (PHD Finger Protein 2 (PHF2))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PHF2 antibody is un-conjugated
- 应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)
- 纯化方法
- Immunogen affinity purified
- 纯度
- ≥95 % as determined by SDS-PAGE
- 免疫原
- PHD finger protein 2
- 亚型
- IgG
- Top Product
- Discover our top product PHF2 Primary Antibody
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anti-PHD Finger Protein 2 (PHF2) (AA 2-100) antibody
PHF2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3E7 unconjugated
anti-PHD Finger Protein 2 (PHF2) (AA 936-985) antibodyPHF2 适用: 人, 兔 WB 宿主: 兔 Polyclonal unconjugated
anti-PHD Finger Protein 2 (PHF2) (Middle Region) antibodyPHF2 适用: 人, 兔, Cow, 马, Saccharomyces cerevisiae WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB: 1:200-1:1000, IP: 1:500-1:1000, IHC: 1:20-1:200
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
- 有效期
- 12 months
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- 抗原
- PHF2 (PHD Finger Protein 2 (PHF2))
- 别名
- PHF2 (PHF2 产品)
- 别名
- CENP-35 antibody, GRC5 antibody, JHDM1E antibody, im:4200679 antibody, phf8 antibody, wu:fa14c10 antibody, PHD finger protein 2 antibody, PHF2 antibody, Phf2 antibody, phf2 antibody
- 背景
- Synonyms:GRC5, JHDM1E, KIAA0662, PHD finger protein 2, PHF2 Background:Lysine demethylase that demethylates both histones and non-histone proteins. Enzymatically inactive by itself, and becomes active following phosphorylation by PKA: forms a complex with ARID5B and mediates demethylation of methylated ARID5B. Demethylation of ARID5B leads to target the PHF2-ARID5B complex to target promoters, where PHF2 mediates demethylation of dimethylated 'Lys-9' of histone H3(H3K9me2), followed by transcription activation of target genes. The PHF2-ARID5B complex acts as a coactivator of HNF4A in liver. PHF2 is recruited to trimethylated 'Lys-4' of histone H3(H3K4me3) at rDNA promoters and promotes expression of rDNA.
- 分子量
- 100 kDa, 150 kDa
- 基因ID
- 5253
- UniProt
- O75151
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