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PELI2 抗体

PELI2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7117276
发货至: 中国
  • 抗原 See all PELI2 抗体
    PELI2 (Pellino Homolog 2 (Drosophila) (PELI2))
    适用
    • 12
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 11
    • 1
    克隆类型
    • 12
    多克隆
    标记
    • 7
    • 1
    • 1
    • 1
    • 1
    • 1
    This PELI2 antibody is un-conjugated
    应用范围
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
    纯化方法
    Immunogen affinity purified
    纯度
    ≥95 % as determined by SDS-PAGE
    免疫原
    pellino homolog 2(Drosophila)
    亚型
    IgG
    Top Product
    Discover our top product PELI2 Primary Antibody
  • 应用备注
    WB: 1:500-1:2000, IHC: 1:20-1:200, IF: 1:20-1:200
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    有效期
    12 months
  • 抗原
    PELI2 (Pellino Homolog 2 (Drosophila) (PELI2))
    别名
    PELI2 (PELI2 产品)
    别名
    AW047589 antibody, BB129927 antibody, pellino 2 antibody, pellino E3 ubiquitin protein ligase family member 2 antibody, Peli2 antibody, PELI2 antibody
    背景
    Synonyms: Background:E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. Involved in the TLR and IL-1 signaling pathways via interaction with the complex containing IRAK kinases and TRAF6. Mediates IL1B-induced IRAK1 'Lys-63'-linked polyubiquitination and possibly 'Lys-48'-linked ubiquitination. May be important for LPS-and IL1B-induced MAP3K7-dependent, but not MAP3K3-dependent, NF-kappa-B activation. Can activate the MAP(mitogen activated protein) kinase pathway leading to activation of ELK1.
    分子量
    45-50 kDa
    基因ID
    57161
    UniProt
    Q9HAT8
    途径
    Activation of Innate immune Response, Toll-Like Receptors Cascades
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