PELI2 抗体
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- 抗原 See all PELI2 抗体
- PELI2 (Pellino Homolog 2 (Drosophila) (PELI2))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PELI2 antibody is un-conjugated
- 应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
- 纯化方法
- Immunogen affinity purified
- 纯度
- ≥95 % as determined by SDS-PAGE
- 免疫原
- pellino homolog 2(Drosophila)
- 亚型
- IgG
- Top Product
- Discover our top product PELI2 Primary Antibody
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anti-Pellino Homolog 2 (Drosophila) (PELI2) (AA 1-420) antibody
PELI2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Pellino Homolog 2 (Drosophila) (PELI2) (N-Term) antibodyPELI2 适用: 人, 小鼠, 大鼠, Pig, 兔, Cow, 斑马鱼, 犬, 豚鼠, 马 WB 宿主: 兔 Polyclonal unconjugated
anti-Pellino Homolog 2 (Drosophila) (PELI2) (AA 22-51), (N-Term) antibodyPELI2 适用: 人 WB, EIA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB: 1:500-1:2000, IHC: 1:20-1:200, IF: 1:20-1:200
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
- 有效期
- 12 months
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- 抗原
- PELI2 (Pellino Homolog 2 (Drosophila) (PELI2))
- 别名
- PELI2 (PELI2 产品)
- 背景
- Synonyms: Background:E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. Involved in the TLR and IL-1 signaling pathways via interaction with the complex containing IRAK kinases and TRAF6. Mediates IL1B-induced IRAK1 'Lys-63'-linked polyubiquitination and possibly 'Lys-48'-linked ubiquitination. May be important for LPS-and IL1B-induced MAP3K7-dependent, but not MAP3K3-dependent, NF-kappa-B activation. Can activate the MAP(mitogen activated protein) kinase pathway leading to activation of ELK1.
- 分子量
- 45-50 kDa
- 基因ID
- 57161
- UniProt
- Q9HAT8
- 途径
- Activation of Innate immune Response, Toll-Like Receptors Cascades
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