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MMP2 抗体 (AA 401-500)

Name: MMP2 抗体 (AA 401-500)
SKU: ABIN707426
Availability: OutOfStock

MMP2 适用: 人, 小鼠, 大鼠, 兔 WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

Rabbit heart lysates probed with Anti-MMP-2 Polyclonal Antibody, Unconjugated (ABIN707426) at 1:300 in 4˚C. (MMP2 抗体 (AA 401-500))

Formalin-fixed and paraffin embedded human laryngeal carcinoma labeled with Anti-MMP-2 Polyclonal Antibody, Unconjugated at 1:200 followed by conjugation to the secondary antibody and DAB staining. (MMP2 抗体 (AA 401-500))

IHC (p)

Formalin-fixed and paraffin embedded human lung carcinoma labeled with Anti-MMP-2 Polyclonal Antibody, Unconjugated at 1:200 followed by conjugation to the secondary antibody and DAB staining. (MMP2 抗体 (AA 401-500))

IHC (p)

Paraformaldehyde-fixed, paraffin embedded rat bladder tissue, Antigen retrieval by boiling in sodium citrate buffer (pH6. (MMP2 抗体 (AA 401-500))

IHC (p)

4 images

(10 references)

产品编号 ABIN707426

发货至: 中国

Datasheet as PDF

抗原 See all MMP2 抗体

MMP2 (Matrix Metalloproteinase 2 (MMP2))
抗原表位
16

16

15

11

11

8

6

6

6

6

5

4

4

4

3

3

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1
AA 401-500
适用
149

80

65

49

7

5

5

3

2

2

2

1
人, 小鼠, 大鼠, 兔
宿主
123

42
兔
Compatible Secondaries
克隆类型
122

43
多克隆
标记
72

14

13

12

5

3

3

3

3

3

3

3

3

3

3

3

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This MMP2 antibody is un-conjugated
应用范围
130

54

51

38

38

34

28

25

18

14

13

4

3

3

1

1
Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

交叉反应

人, 小鼠, 兔, 大鼠

预测反应

Cow,Sheep,Pig,Horse

纯化方法

Purified by Protein A.

免疫原

KLH conjugated synthetic peptide derived from human MMP-2

亚型

IgG

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anti-Matrix Metalloproteinase 2 (MMP2) (AA 31-109) antibody
MMP2 适用: 人, 小鼠, 大鼠, 兔 WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Matrix Metalloproteinase 2 (MMP2) (AA 40-280) antibody
MMP2 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Matrix Metalloproteinase 2 (MMP2) antibody
MMP2 适用: 人 WB, IP, IF, IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Matrix Metalloproteinase 2 (MMP2) (AA 580-660) antibody
MMP2 适用: 人, 小鼠, 大鼠, 猴 WB, ELISA, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Matrix Metalloproteinase 2 (MMP2) (AA 110-660) antibody
MMP2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Matrix Metalloproteinase 2 (MMP2) (AA 9-140) antibody
MMP2 适用: 人, 小鼠 WB, ELISA, IHC, FACS, ICC 宿主: 小鼠 Monoclonal 2B11E6 unconjugated

anti-Matrix Metalloproteinase 2 (MMP2) (C-Term) antibody
MMP2 适用: 人, 小鼠, 大鼠, 兔, Cow, 犬, 绵羊, 豚鼠, 马 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Matrix Metalloproteinase 2 (MMP2) (AA 110-660) antibody
MMP2 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C1 unconjugated

anti-Matrix Metalloproteinase 2 (MMP2) (AA 242-396) antibody
MMP2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4D1E2 unconjugated

anti-Matrix Metalloproteinase 2 (MMP2) (AA 561-660) antibody
MMP2 适用: 人, 小鼠, 兔 WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

应用备注

WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

限制

仅限研究用
状态

Liquid

浓度

1 μg/μL

缓冲液

0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

储存液

ProClin

注意事项

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

有效期

12 months
Bi, Zhang, Du, Zhang, Deng, Liu, Zhang: "Peripheral serotonin regulates postoperative intra-abdominal adhesion formation in mice." in: Scientific reports, Vol. 7, Issue 1, pp. 10001, (2019) (PubMed).

Gasparski, Ozarkar, Beningo: "Transient mechanical strain promotes the maturation of invadopodia and enhances cancer cell invasion in vitro." in: Journal of cell science, Vol. 130, Issue 11, pp. 1965-1978, (2018) (PubMed).

Wang, Nikhil, Viccaro, Chang, White, Shah: "Phosphorylation-dependent regulation of ALDH1A1 by Aurora kinase A: insights on their synergistic relationship in pancreatic cancer." in: BMC biology, Vol. 15, Issue 1, pp. 10, (2017) (PubMed).

Wang, Nikhil, Viccaro, Chang, Jacobsen, Sandusky, Shah: "The Aurora-A-Twist1 axis promotes highly aggressive phenotypes in pancreatic carcinoma." in: Journal of cell science, Vol. 130, Issue 6, pp. 1078-1093, (2017) (PubMed).

Liu, Chi, Lu, Zhang, Yamakawa: "Reversion-inducing-cysteine-rich Protein with Kazal Motif Is Involved in Intimal Hyperplasia in Carotid Arteries: A New Insight in the Prevention of Restenosis after Vascular Angioplasty." in: Annals of vascular surgery, Vol. 29, Issue 6, pp. 1293-9, (2015) (PubMed).

Cavdar, Ozbal, Celik, Ergur, Guneli, Ural, Camsari, Guner: "The effects of alpha-lipoic acid on MMP-2 and MMP-9 activities in a rat renal ischemia and re-perfusion model." in: Biotechnic & histochemistry : official publication of the Biological Stain Commission, Vol. 89, Issue 4, pp. 304-14, (2014) (PubMed).

Fan, Han, Zhu, Zhang, Zhu: "Ultrasensitive photoelectrochemical immunoassay for matrix metalloproteinase-2 detection based on CdS:Mn/CdTe cosensitized TiO2 nanotubes and signal amplification of SiO2@Ab2 conjugates." in: Analytical chemistry, Vol. 86, Issue 24, pp. 12398-405, (2014) (PubMed).
抗原

MMP2 (Matrix Metalloproteinase 2 (MMP2))

别名

MMP-2 (MMP2 产品)

别名

2-MMP antibody, CG1794 antibody, DM2-MMP antibody, Dm2-MMP antibody, Dmel\\CG1794 antibody, MMP2 antibody, anon-WO0118547.84 antibody, dm-2MMP antibody, dmmp2 antibody, l(2)02353 antibody, mmp2 antibody, wu:fa99h12 antibody, wu:fk89d01 antibody, fgmmp-2 antibody, Mmp-2 antibody, LOC100135793 antibody, Clg4a antibody, GelA antibody, MMP-2 antibody, CLG4 antibody, CLG4A antibody, MMP-II antibody, MONA antibody, TBE-1 antibody, matrix metallopeptidase 2 antibody, Matrix metalloproteinase 2 antibody, matrix metalloproteinase 2 antibody, matrix metalloproteinase-2 antibody, MMP2 antibody, Mmp2 antibody, mmp2 antibody, LOC657982 antibody, LOC100135793 antibody

背景

Synonyms: CLG4, MONA, CLG4A, MMP-2, TBE-1, MMP-II, 72 kDa type IV collagenase, 72 kDa gelatinase, Gelatinase A, Matrix metalloproteinase-2, MMP2
Background: Ubiquitinous metalloproteinase that is involved in diverse functions such as remodeling of the vasculature, angiogenesis, tissue repair, tumor invasion, inflammation, and atherosclerotic plaque rupture. As well as degrading extracellular matrix proteins, can also act on several nonmatrix proteins such as big endothelial 1 and beta-type CGRP promoting vasoconstriction. Also cleaves KISS at a Gly-|-Leu bond. Appears to have a role in myocardial cell death pathways. Contributes to myocardial oxidative stress by regulating the activity of GSK3beta. Cleaves GSK3beta in vitro. Involved in the formation of the fibrovascular tissues in association with MMP14. PEX, the C-terminal non-catalytic fragment of MMP2, posseses anti-angiogenic and anti-tumor properties and inhibits cell migration and cell adhesion to FGF2 and vitronectin. Ligand for integrinv/beta3 on the surface of blood vessels. Isoform 2: Mediates the proteolysis of CHUK/IKKA and initiates a primary innate immune response by inducing mitochondrial-nuclear stress signaling with activation of the pro-inflammatory NF-kappaB, NFAT and IRF transcriptional pathways.

基因ID

4313

UniProt

P08253

途径

Activation of Innate immune Response