OSBPL3 抗体 (AA 370-520)
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北京 101111
Quick Overview for OSBPL3 抗体 (AA 370-520) (ABIN7117176)
抗原
See all OSBPL3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 370-520
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原理
- OSBPL3 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
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Immunogen sequence: 370-520aa
Immunogen: oxysterol binding protein-like 3
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亚型
- IgG
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anti-Oxysterol Binding Protein-Like 3 (OSBPL3) (N-Term) antibody
Verified OSBPL3 适用: 人 ELISA, FACS, IF 宿主: 山羊 Polyclonal unconjugated
anti-Oxysterol Binding Protein-Like 3 (OSBPL3) (AA 370-520) antibodyOSBPL3 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Oxysterol Binding Protein-Like 3 (OSBPL3) (AA 1-820) antibodyOSBPL3 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Oxysterol Binding Protein-Like 3 (OSBPL3) (N-Term) antibodyOSBPL3 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Oxysterol Binding Protein-Like 3 (OSBPL3) (N-Term) antibodyOSBPL3 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Oxysterol Binding Protein-Like 3 (OSBPL3) (N-Term) antibodyOSBPL3 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:500-1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- OSBPL3 (Oxysterol Binding Protein-Like 3 (OSBPL3))
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别名
- OSBPL3
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背景
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Synonyms: Oxysterol-binding protein-related protein 3 (ORP-3, OSBP-related protein 3)|OSBPL3|KIAA0704|ORP3|OSBP3
Background: Phosphoinositide-binding protein which associates with both cell and endoplasmic reticulum(ER) membranes(PubMed:16143324). Can bind to the ER membrane protein VAPA and recruit VAPA to plasma membrane sites, thus linking these intracellular compartments(PubMed:25447204). The ORP3-VAPA complex stimulates RRAS signaling which in turn attenuates integrin beta-1(ITGB1) activation at the cell surface(PubMed:18270267, PubMed:25447204). With VAPA, may regulate ER morphology(PubMed:16143324). Has a role in regulation of the actin cytoskeleton, cell polarity and cell adhesion(PubMed:18270267). Binds to phosphoinositides with preference for PI(3,4)P2 and PI(3,4,5)P3(PubMed:16143324). Also binds 25-hydroxycholesterol and cholesterol(PubMed:17428193).
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分子量
- 101 kDa
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基因ID
- 26031
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UniProt
- Q9H4L5
抗原
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