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OSBPL3 抗体

OSBPL3 适用: 小鼠, 人, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7117176
发货至: 中国
  • 抗原 See all OSBPL3 抗体
    OSBPL3 (Oxysterol Binding Protein-Like 3 (OSBPL3))
    适用
    • 19
    • 18
    • 9
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    • 1
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    小鼠, 人, 大鼠
    宿主
    • 21
    • 2
    • 1
    克隆类型
    • 24
    多克隆
    标记
    • 10
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    This OSBPL3 antibody is un-conjugated
    应用范围
    • 13
    • 13
    • 8
    • 5
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA
    纯化方法
    Immunogen affinity purified
    纯度
    ≥95 % as determined by SDS-PAGE
    免疫原
    oxysterol binding protein-like 3
    亚型
    IgG
    Top Product
    Discover our top product OSBPL3 Primary Antibody
  • 应用备注
    WB: 1:500-1:2000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    有效期
    12 months
  • 抗原
    OSBPL3 (Oxysterol Binding Protein-Like 3 (OSBPL3))
    别名
    OSBPL3 (OSBPL3 产品)
    别名
    osbpl3 antibody, zgc:101089 antibody, OSBPL3 antibody, ORP-3 antibody, ORP3 antibody, OSBP3 antibody, 1200014M06Rik antibody, 6720421I08Rik antibody, A530055M08 antibody, RGD1564287 antibody, oxysterol binding protein like 3 antibody, oxysterol binding protein-like 3a antibody, oxysterol binding protein-like 3 antibody, OSBPL3 antibody, osbpl3a antibody, osbpl3 antibody, Osbpl3 antibody
    背景
    Synonyms:KIAA0704, ORP3, OSBP3 Background:Phosphoinositide-binding protein which associates with both cell and endoplasmic reticulum(ER) membranes(PubMed:16143324). Can bind to the ER membrane protein VAPA and recruit VAPA to plasma membrane sites, thus linking these intracellular compartments(PubMed:25447204). The ORP3-VAPA complex stimulates RRAS signaling which in turn attenuates integrin beta-1(ITGB1) activation at the cell surface(PubMed:18270267, PubMed:25447204). With VAPA, may regulate ER morphology(PubMed:16143324). Has a role in regulation of the actin cytoskeleton, cell polarity and cell adhesion(PubMed:18270267). Binds to phosphoinositides with preference for PI(3,4)P2 and PI(3,4,5)P3(PubMed:16143324). Also binds 25-hydroxycholesterol and cholesterol(PubMed:17428193).
    分子量
    101 kDa
    基因ID
    26031
    UniProt
    Q9H4L5
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