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OSBPL3 抗体

This anti-OSBPL3 antibody is a 兔 多克隆 antibody detecting OSBPL3 in WB 和 ELISA. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7117176
发货至: 中国

Quick Overview for OSBPL3 抗体 (ABIN7117176)

抗原

See all OSBPL3 抗体
OSBPL3 (Oxysterol Binding Protein-Like 3 (OSBPL3))

适用

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  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 21
  • 2
  • 1

克隆类型

  • 24
多克隆

标记

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  • 1
  • 1
  • 1
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This OSBPL3 antibody is un-conjugated

应用范围

  • 13
  • 13
  • 8
  • 5
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  • 3
  • 1
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  • 1
  • 1
  • 1
Western Blotting (WB), ELISA
  • 纯化方法

    Immunogen affinity purified

    纯度

    ≥95 % as determined by SDS-PAGE

    免疫原

    oxysterol binding protein-like 3

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:2000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

    有效期

    12 months
  • 抗原

    OSBPL3 (Oxysterol Binding Protein-Like 3 (OSBPL3))

    别名

    OSBPL3

    背景

    Synonyms:KIAA0704, ORP3, OSBP3 Background:Phosphoinositide-binding protein which associates with both cell and endoplasmic reticulum(ER) membranes(PubMed:16143324). Can bind to the ER membrane protein VAPA and recruit VAPA to plasma membrane sites, thus linking these intracellular compartments(PubMed:25447204). The ORP3-VAPA complex stimulates RRAS signaling which in turn attenuates integrin beta-1(ITGB1) activation at the cell surface(PubMed:18270267, PubMed:25447204). With VAPA, may regulate ER morphology(PubMed:16143324). Has a role in regulation of the actin cytoskeleton, cell polarity and cell adhesion(PubMed:18270267). Binds to phosphoinositides with preference for PI(3,4)P2 and PI(3,4,5)P3(PubMed:16143324). Also binds 25-hydroxycholesterol and cholesterol(PubMed:17428193).

    分子量

    101 kDa

    基因ID

    26031

    UniProt

    Q9H4L5
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