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OSBP 抗体

OSBP 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IP 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7117171
发货至: 中国
  • 抗原 See all OSBP 抗体
    OSBP (Oxysterol Binding Protein (OSBP))
    适用
    • 20
    • 5
    • 5
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 16
    • 3
    • 1
    克隆类型
    • 17
    • 3
    多克隆
    标记
    • 17
    • 1
    • 1
    • 1
    This OSBP antibody is un-conjugated
    应用范围
    • 15
    • 6
    • 6
    • 4
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)
    纯化方法
    Immunogen affinity purified
    纯度
    ≥95 % as determined by SDS-PAGE
    免疫原
    oxysterol binding protein
    亚型
    IgG
    Top Product
    Discover our top product OSBP Primary Antibody
  • 应用备注
    WB: 1:500-1:2000, IP: 1:200-1:1000, IHC: 1:20-1:200
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    有效期
    12 months
  • 抗原
    OSBP (Oxysterol Binding Protein (OSBP))
    别名
    OSBP (OSBP 产品)
    别名
    CG6708 antibody, Dmel\\CG6708 antibody, OSBP-Dm antibody, osbp antibody, OSBP1 antibody, 1110018F06Rik antibody, AW559088 antibody, mKIAA4220 antibody, Oxysterol binding protein antibody, oxysterol binding protein antibody, Osbp antibody, OSBP antibody
    背景
    Synonyms:OSBP1 Background:Lipid transporter involved in lipid countertransport between the Golgi complex and membranes of the endoplasmic reticulum: specifically exchanges sterol with phosphatidylinositol 4-phosphate(PI4P), delivering sterol to the Golgi in exchange for PI4P, which is degraded by the SAC1/SACM1L phosphatase in the endoplasmic reticulum(PubMed:24209621). Binds cholesterol and a range of oxysterols including 25-hydroxycholesterol(PubMed:15746430, PubMed:17428193). Cholesterol binding promotes the formation of a complex with PP2A and a tyrosine phosphatase which dephosphorylates ERK1/2, whereas 25-hydroxycholesterol causes its disassembly(PubMed:15746430). Regulates cholesterol efflux by decreasing ABCA1 stability(PubMed:18450749).
    分子量
    89 kDa
    基因ID
    5007
    UniProt
    P22059
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