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NMRAL1 抗体

NMRAL1 适用: 人, 大鼠, 小鼠 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7116912
发货至: 中国
  • 抗原 See all NMRAL1 抗体
    NMRAL1 (NmrA-Like Family Domain Containing 1 (NMRAL1))
    适用
    • 11
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 大鼠, 小鼠
    宿主
    • 10
    • 2
    克隆类型
    • 12
    多克隆
    标记
    • 8
    • 2
    • 1
    • 1
    This NMRAL1 antibody is un-conjugated
    应用范围
    • 7
    • 6
    • 1
    • 1
    ELISA, Western Blotting (WB), Immunohistochemistry (IHC)
    纯化方法
    Immunogen affinity purified
    纯度
    ≥95 % as determined by SDS-PAGE
    免疫原
    NmrA-like family domain containing 1
    亚型
    IgG
    Top Product
    Discover our top product NMRAL1 Primary Antibody
  • 应用备注
    WB: 1:500-1:2000, IHC: 1:20-1:200
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    有效期
    12 months
  • 抗原
    NMRAL1 (NmrA-Like Family Domain Containing 1 (NMRAL1))
    别名
    NMRAL1 (NMRAL1 产品)
    别名
    HSCARG antibody, SDR48A1 antibody, 1110025F24Rik antibody, AI256624 antibody, RGD1311451 antibody, NmrA like redox sensor 1 antibody, NmrA-like family domain containing 1 antibody, NMRAL1 antibody, Nmral1 antibody
    背景
    Synonyms:HSCARG Background:Redox sensor protein. Undergoes restructuring and subcellular redistribution in response to changes in intracellular NADPH/NADP(+) levels. At low NADPH concentrations the protein is found mainly as a monomer, and binds argininosuccinate synthase(ASS1), the enzyme involved in nitric oxide synthesis. Association with ASS1 impairs its activity and reduces the production of nitric oxide, which subsecuently prevents apoptosis. Under normal NADPH concentrations, the protein is found as a dimer and hides the binding site for ASS1. The homodimer binds one molecule of NADPH. Has higher affinity for NADPH than for NADP(+). Binding to NADPH is necessary to form a stable dimer.
    分子量
    33 kDa
    基因ID
    57407
    UniProt
    Q9HBL8
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