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NGEF 抗体
NGEF
适用: 人, 小鼠
WB, ELISA, IHC, IP
宿主: 兔
Polyclonal
unconjugated
NGEF抗体详情
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抗原
See all NGEF 抗体
NGEF
(Neuronal Guanine Nucleotide Exchange Factor (NGEF))
适用
All reactivities for NGEF 抗体
人, 小鼠
宿主
All hosts for NGEF 抗体
兔
克隆类型
All clonalities for NGEF 抗体
多克隆
标记
All conjugates for NGEF 抗体
This NGEF antibody is un-conjugated
应用范围
All applications for NGEF 抗体
Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)
纯化方法
Immunogen affinity purified
纯度
≥95 % as determined by SDS-PAGE
免疫原
neuronal guanine nucleotide exchange factor
亚型
IgG
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Discover our top product NGEF Primary Antibody
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使用细节
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应用备注
WB: 1:500-1:1000, IP: 1:500-1:1000, IHC: 1:50-1:500
限制
仅限研究用
贮存及处理
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状态
Liquid
缓冲液
PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
-20 °C
储存方法
-20°C for 12 months (Avoid repeated freeze / thaw cycles.)
有效期
12 months
NGEF目标详情
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抗原
NGEF
(Neuronal Guanine Nucleotide Exchange Factor (NGEF))
别名
NGEF (NGEF 产品 )
别名
Ephexin-1 antibody, ARHGEF27 antibody, EPHEXIN antibody, Tims2 antibody, ephexin antibody, Besh3 antibody, ephexin-1 antibody, neuronal guanine nucleotide exchange factor antibody, NGEF antibody, Ngef antibody
背景
Synonyms: Background:Acts as a guanine nucleotide exchange factor(GEF) which differentially activates the GTPases RHOA, RAC1 and CDC42. Plays a role in axon guidance regulating ephrin-induced growth cone collapse and dendritic spine morphogenesis. Upon activation by ephrin through EPHA4, the GEF activity switches toward RHOA resulting in its activation. Activated RHOA promotes cone retraction at the expense of RAC1-and CDC42-stimulated growth cone extension(By similarity).
分子量
75 kDa
基因ID
25791
UniProt
Q8N5V2
途径
Neurotrophin Signaling Pathway
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