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MTM1 抗体

This anti-MTM1 antibody is a 兔 多克隆 antibody detecting MTM1 in WB, ELISA 和 IHC. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7116648
发货至: 中国

Quick Overview for MTM1 抗体 (ABIN7116648)

抗原

See all MTM1 抗体
MTM1 (Myotubularin 1 (MTM1))

适用

  • 44
  • 37
  • 24
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 41
  • 4
  • 1

克隆类型

  • 43
  • 3
多克隆

标记

  • 20
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This MTM1 antibody is un-conjugated

应用范围

  • 40
  • 14
  • 13
  • 13
  • 5
  • 5
  • 2
  • 2
  • 1
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
  • 纯化方法

    Immunogen affinity purified

    纯度

    ≥95 % as determined by SDS-PAGE

    免疫原

    myotubularin 1

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:2000, IHC: 1:20-1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

    有效期

    12 months
  • 抗原

    MTM1 (Myotubularin 1 (MTM1))

    别名

    MTM1

    背景

    Synonyms:CG2 Background:Lipid phosphatase which dephosphorylates phosphatidylinositol 3-monophosphate(PI3P) and phosphatidylinositol 3,5-bisphosphate(PI(3,5)P2). Has also been shown to dephosphorylate phosphotyrosine-and phosphoserine-containing peptides. Negatively regulates EGFR degradation through regulation of EGFR trafficking from the late endosome to the lysosome. Plays a role in vacuolar formation and morphology. Regulates desmin intermediate filament assembly and architecture. Plays a role in mitochondrial morphology and positioning. Required for skeletal muscle maintenance but not for myogenesis.

    分子量

    63 kDa

    基因ID

    4534

    UniProt

    Q13496

    途径

    Inositol Metabolic Process, Skeletal Muscle Fiber Development
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