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Myosin VIIA 抗体

MYO7A 适用: 人, 小鼠, 大鼠 ELISA, WB, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7116628
发货至: 中国
  • 抗原 See all Myosin VIIA (MYO7A) 抗体
    Myosin VIIA (MYO7A)
    适用
    • 35
    • 25
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 33
    • 2
    克隆类型
    • 33
    • 2
    多克隆
    标记
    • 11
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    This Myosin VIIA antibody is un-conjugated
    应用范围
    • 14
    • 13
    • 13
    • 6
    • 3
    • 3
    • 3
    • 2
    • 1
    ELISA, Western Blotting (WB), Immunofluorescence (IF)
    纯化方法
    Immunogen affinity purified
    纯度
    ≥95 % as determined by SDS-PAGE
    免疫原
    myosin VIIA
    亚型
    IgG
    Top Product
    Discover our top product MYO7A Primary Antibody
  • 应用备注
    WB: 1:500-1:2000, IF: 1:20-1:200
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    有效期
    12 months
  • 抗原
    Myosin VIIA (MYO7A)
    别名
    MYO7A (MYO7A 产品)
    背景
    Synonyms:USH1B Background:Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails bind to membranous compartments, which are then moved relative to actin filaments. In the retina, plays an important role in the renewal of the outer photoreceptor disks. Plays an important role in the distribution and migration of retinal pigment epithelial(RPE) melanosomes and phagosomes, and in the regulation of opsin transport in retinal photoreceptors. In the inner ear, plays an important role in differentiation, morphogenesis and organization of cochlear hair cell bundles. Involved in hair-cell vesicle trafficking of aminoglycosides, which are known to induce ototoxicity(By similarity). Motor protein that is a part of the functional network formed by USH1C, USH1G, CDH23 and MYO7A that mediates mechanotransduction in cochlear hair cells. Required for normal hearing.
    分子量
    160-255kd
    基因ID
    4647
    UniProt
    Q13402
    途径
    Sensory Perception of Sound
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