MPZL1 antibody, MPZL1b antibody, PZR antibody, PZR1b antibody, PZRa antibody, PZRb antibody, 1110007A10Rik antibody, myelin protein zero like 1 antibody, myelin protein zero-like 1 antibody, MPZL1 antibody, Mpzl1 antibody
背景
Synonyms:PZR Background:Cell surface receptor, which is involved in signal transduction processes. Recruits PTPN11/SHP-2 to the cell membrane and is a putative substrate of PTPN11/SHP-2. Is a major receptor for concanavalin-A(ConA) and is involved in cellular signaling induced by ConA, which probably includes Src family tyrosine-protein kinases. Isoform 3 seems to have a dominant negative role, it blocks tyrosine phosphorylation of MPZL1 induced by ConA. Isoform 1, but not isoform 2 and isoform 3, may be involved in regulation of integrin-mediated cell motility.