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MMS19 抗体

MMS19 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, IHC 宿主: 小鼠 Monoclonal 6H1 unconjugated
产品编号 ABIN7116477
发货至: 中国
  • 抗原 See all MMS19 抗体
    MMS19 (MMS19 Nucleotide Excision Repair Homolog (MMS19))
    适用
    人, 小鼠, 大鼠
    宿主
    • 25
    • 3
    小鼠
    克隆类型
    • 27
    • 1
    单克隆
    标记
    • 9
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MMS19 antibody is un-conjugated
    应用范围
    • 28
    • 13
    • 13
    • 11
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC)
    纯化方法
    Protein A+G purification
    纯度
    ≥95 % as determined by SDS-PAGE
    免疫原
    MMS19 nucleotide excision repair homolog(S. cerevisiae)
    克隆位点
    6H1
    亚型
    IgG2a
    Top Product
    Discover our top product MMS19 Primary Antibody
  • 应用备注
    WB: 1:1000-1:4000, IHC: 1:20-1:200, IF: 1:20-1:200
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    有效期
    12 months
  • 抗原
    MMS19 (MMS19 Nucleotide Excision Repair Homolog (MMS19))
    别名
    MMS19 (MMS19 产品)
    别名
    MET18 antibody, MMS19L antibody, hMMS19 antibody, 2410001K24Rik antibody, 2610042O15Rik antibody, AI316855 antibody, C79368 antibody, C86341 antibody, Mms19l antibody, mms19 antibody, mms19l antibody, MMS19 homolog, cytosolic iron-sulfur assembly component antibody, MMS19 (MET18 S. cerevisiae) antibody, MMS19 homolog, cytosolic iron-sulfur assembly component L homeolog antibody, MMS19 antibody, Mms19 antibody, mms19.L antibody
    背景
    Synonyms:MMS19L Background:Key component of the cytosolic iron-sulfur protein assembly(CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into apoproteins specifically involved in DNA metabolism and genomic integrity. In the CIA complex, MMS19 acts as an adapter between early-acting CIA components and a subset of cellular target iron-sulfur proteins such as ERCC2/XPD, FANCJ and RTEL1, thereby playing a key role in nucleotide excision repair(NER) and RNA polymerase II(POL II) transcription. As part of the mitotic spindle-associated MMXD complex, plays a role in chromosome segregation, probably by facilitating iron-sulfur cluster assembly into ERCC2/XPD. Indirectly acts as a transcriptional coactivator of estrogen receptor(ER), via its role in iron-sulfur insertion into some component of the TFIIH-machinery.
    分子量
    103 kDa
    基因ID
    64210
    UniProt
    Q96T76
    途径
    Nuclear Hormone Receptor Binding
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