MAPKBP1 抗体
Quick Overview for MAPKBP1 抗体 (ABIN7116438)
抗原
See all MAPKBP1 抗体适用
宿主
克隆类型
标记
应用范围
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- mitogen-activated protein kinase binding protein 1
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亚型
- IgG
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anti-Mitogen-Activated Protein Kinase Binding Protein 1 (MAPKBP1) (AA 1-100) antibody
MAPKBP1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Binding Protein 1 (MAPKBP1) (AA 1-1015) antibodyMAPKBP1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Binding Protein 1 (MAPKBP1) (N-Term) antibodyMAPKBP1 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, Chimpanzee, Gibbon, Gorilla, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Binding Protein 1 (MAPKBP1) (N-Term) antibodyMAPKBP1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Binding Protein 1 (MAPKBP1) (N-Term) antibodyMAPKBP1 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:200 - 1:500, IHC: 1:50 - 1:100
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3 ,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
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有效期
- 12 months
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- MAPKBP1 (Mitogen-Activated Protein Kinase Binding Protein 1 (MAPKBP1))
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别名
- MAPKBP1
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背景
- Synonyms:JNKBP1, KIAA0596 Background:MAP kinases play a significant role in many biological processes, including cell adhesion and spreading, cell differentiation and apoptosis. MAPKBP-1 (mitogen-activated protein kinase binding protein 1), also known as JNKBP-1, is a 1, 514 amino acid protein that contains twelve WD repeats. Induced by TRAF2 (TNF receptor-associated factor 2) and Tak1 (TGF-β-activated kinase 1), MAPKBP-1 is thought to act an adaptor protein for NFκB (nuclear factor κ-B) activation. MAPKBP-1 interacts with JNK3 and may promote TRAF2 polyubiquitination. MAPKBP-1 exists as six alternatively spliced variants and is encoded by a gene located on human chromosome 15. Human chromosome 15 houses over 700 genes and comprises nearly 3 % of the human genome. Angelman syndrome, Prader-Willi syndrome, Tay-Sachs disease and Marfan syndrome are all associated with defects in chromosome 15-localized genes.
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分子量
- 165 kDa
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基因ID
- 23005
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UniProt
- O60336
抗原
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