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C20orf72 抗体

MGME1 适用: 人, 小鼠 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7116334
发货至: 中国
  • 抗原 See all C20orf72 (MGME1) products
    C20orf72 (MGME1) (Mitochondrial Genome Maintenance Exonuclease 1 (MGME1))
    适用
    • 28
    • 7
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 28
    克隆类型
    • 28
    多克隆
    标记
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This C20orf72 antibody is un-conjugated
    应用范围
    • 17
    • 13
    • 13
    • 7
    • 3
    • 3
    • 1
    • 1
    ELISA, Western Blotting (WB), Immunohistochemistry (IHC)
    纯化方法
    Immunogen affinity purified
    纯度
    ≥95 % as determined by SDS-PAGE
    免疫原
    chromosome 20 open reading frame 72
    亚型
    IgG
  • 应用备注
    WB: 1:500-1:2000, IHC: 1:20-1:200
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    有效期
    12 months
  • 抗原
    C20orf72 (MGME1) (Mitochondrial Genome Maintenance Exonuclease 1 (MGME1))
    别名
    MGME1 (MGME1 产品)
    别名
    C20orf72 antibody, DDK1 antibody, MTDPS11 antibody, bA504H3.4 antibody, mitochondrial genome maintenance exonuclease 1 antibody, MGME1 antibody
    背景
    Synonyms:C20orf72, DDK1 Background:Metal-dependent single-stranded DNA(ssDNA) exonuclease involved in mitochondrial genome maintenance. Has preference for 5'-3' exonuclease activity but is also capable of endoduclease activity on linear substrates. Necessary for maintenance of proper 7S DNA levels. Probably involved in mitochondrial DNA(mtDNA) repair, possibly via the processing of displaced DNA containing Okazaki fragments during RNA-primed DNA synthesis on the lagging strand or via processing of DNA flaps during long-patch base excision repair. Specifically binds 5-hydroxymethylcytosine(5hmC)-containing DNA in stem cells.
    分子量
    36-39 kDa
    基因ID
    92667
    UniProt
    Q9BQP7
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