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MAP4K6 抗体

MINK1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7116324
发货至: 中国
  • 抗原 See all MAP4K6 (MINK1) 抗体
    MAP4K6 (MINK1) (Misshapen-Like Kinase 1 (MINK1))
    适用
    • 29
    • 20
    • 7
    • 7
    • 6
    • 6
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    人, 小鼠, 大鼠
    宿主
    • 29
    克隆类型
    • 29
    多克隆
    标记
    • 17
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    This MAP4K6 antibody is un-conjugated
    应用范围
    • 14
    • 11
    • 10
    • 5
    • 4
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    纯化方法
    Immunogen affinity purified
    纯度
    ≥95 % as determined by SDS-PAGE
    免疫原
    misshapen-like kinase 1(zebrafish)
    亚型
    IgG
    Top Product
    Discover our top product MINK1 Primary Antibody
  • 应用备注
    WB: 1:500-1:2000, IHC: 1:20-1:200
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    有效期
    12 months
  • 抗原
    MAP4K6 (MINK1) (Misshapen-Like Kinase 1 (MINK1))
    别名
    MINK1 (MINK1 产品)
    别名
    MINK1 antibody, MINK antibody, B55 antibody, MAP4K6 antibody, YSK2 antibody, ZC3 antibody, hMINK antibody, hMINKbeta antibody, MEKKK 6 antibody, Map4k6 antibody, RP23-122P1.6 antibody, Ysk2 antibody, misshapen like kinase 1 antibody, misshapen-like kinase 1 antibody, misshapen-like kinase 1 (zebrafish) antibody, MINK1 antibody, Mink1 antibody
    背景
    Synonyms:B55, MAP4K6, Background:Serine/threonine kinase which acts as a negative regulator of Ras-related Rap2-mediated signal transduction to control neuronal structure and AMPA receptor trafficking. Required for normal synaptic density, dendrite complexity, as well as surface AMPA receptor expression in hippocampal neurons. Can activate the JNK and MAPK14/p38 pathways and mediates stimulation of the stress-activated protein kinase MAPK14/p38 MAPK downstream of the Raf/ERK pathway. Phosphorylates: TANC1 upon stimulation by RAP2A, MBP and SMAD1. Has an essential function in negative selection of thymocytes, perhaps by coupling NCK1 to activation of JNK1. Isoform 4 can activate the JNK pathway. Involved in the regulation of actin cytoskeleton reorganization, cell-matrix adhesion, cell-cell adhesion and cell migration.
    分子量
    150 kDa
    基因ID
    50488
    UniProt
    Q8N4C8
    途径
    Synaptic Membrane
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