Synonyms:PGAP5 Background:Metallophosphoesterase required for transport of GPI-anchor proteins from the endoplasmic reticulum to the Golgi. Acts in lipid remodeling steps of GPI-anchor maturation by mediating the removal of a side-chain ethanolamine-phosphate(EtNP) from the second Man(Man2) of the GPI intermediate, an essential step for efficient transport of GPI-anchor proteins.