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MSL1 抗体

MSL1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7116032
发货至: 中国
  • 抗原 See all MSL1 抗体
    MSL1 (Male-Specific Lethal 1 Homolog (MSL1))
    适用
    • 18
    • 3
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    • 1
    • 1
    • 1
    宿主
    • 18
    克隆类型
    • 18
    多克隆
    标记
    • 8
    • 2
    • 2
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    This MSL1 antibody is un-conjugated
    应用范围
    Western Blotting (WB), ELISA
    纯化方法
    Immunogen affinity purified
    纯度
    ≥95 % as determined by SDS-PAGE
    免疫原
    male-specific lethal 1 homolog(Drosophila)
    亚型
    IgG
    Top Product
    Discover our top product MSL1 Primary Antibody
  • 应用备注
    WB: 1:500-1:2000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    有效期
    12 months
  • 抗原
    MSL1 (Male-Specific Lethal 1 Homolog (MSL1))
    别名
    MSL1 (MSL1 产品)
    别名
    MSL-1 antibody, hMSL1 antibody, 2810017F12Rik antibody, 4121402D02Rik antibody, 4930463F05Rik antibody, AA682082 antibody, Msl-1 antibody, male specific lethal 1 homolog antibody, male-specific lethal 1 homolog (Drosophila) antibody, MSL1 antibody, Msl1 antibody
    背景
    Synonyms:MSL1L1 Background:Component of histone acetyltransferase complex responsible for the majority of histone H4 acetylation at 'Lys-16'(H4K16ac) which is implicated in the formation of higher-order chromatin structure. Greatly enhances MSL2 E3 ubiquitin ligase activity, promoting monoubiquitination of histone H2B at 'Lys-34'(H2BK34Ub). This modification in turn stimulates histone H3 methylation at 'Lys-4'(H3K4me) and 'Lys-79'(H3K79me) and leads to gene activation, including that of HOXA9 and MEIS1. In the MSL complex, acts as a scaffold to tether MSL3 and KAT8 together for enzymatic activity regulation.
    分子量
    67 kDa
    基因ID
    339287
    UniProt
    Q68DK7
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