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LRWD1 抗体
LRWD1
适用: 人
WB, ELISA
宿主: 兔
Polyclonal
unconjugated
LRWD1抗体详情
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抗原
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LRWD1
(Leucine-Rich Repeat and WD Repeat-Containing Protein 1 (LRWD1))
适用
All reactivities for LRWD1 抗体
人
宿主
All hosts for LRWD1 抗体
兔
克隆类型
All clonalities for LRWD1 抗体
多克隆
标记
All conjugates for LRWD1 抗体
This LRWD1 antibody is un-conjugated
应用范围
All applications for LRWD1 抗体
Western Blotting (WB), ELISA
纯化方法
Immunogen affinity purified
纯度
≥95 % as determined by SDS-PAGE
免疫原
leucine-rich repeats and WD repeat domain containing 1
亚型
IgG
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Alternatives
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使用细节
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应用备注
WB: 1:500-1:2000
限制
仅限研究用
贮存及处理
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状态
Liquid
缓冲液
PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
-20 °C
储存方法
-20°C for 12 months (Avoid repeated freeze / thaw cycles.)
有效期
12 months
LRWD1目标详情
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抗原
LRWD1
(Leucine-Rich Repeat and WD Repeat-Containing Protein 1 (LRWD1))
别名
LRWD1 (LRWD1 产品 )
别名
CENP-33 antibody, ORCA antibody, 1200011O22Rik antibody, AU042569 antibody, AW548074 antibody, Orca antibody, si:dkey-261j4.9 antibody, wu:fb78b03 antibody, wu:ft31b04 antibody, leucine rich repeats and WD repeat domain containing 1 antibody, leucine-rich repeats and WD repeat domain containing 1 antibody, microRNA 5090 antibody, leucine-rich repeats and WD repeat domain containing 1 L homeolog antibody, LRWD1 antibody, Lrwd1 antibody, lrwd1 antibody, MIR5090 antibody, lrwd1.L antibody
背景
Synonyms:CENP-33, ORCA Background:Required for G1/S transition. Recruits and stabilizes the origin recognition complex(ORC) onto chromatin during G1 to establish pre-replication complex(preRC) and to heterochromatic sites in post-replicated cells. Binds a combination of DNA and histone methylation repressive marks on heterochromatin. Binds histone H3 and H4 trimethylation marks H3K9me3, H3K20me3 and H4K27me3 in a cooperative manner with DNA methylation. Required for silencing of major satellite repeats. May be important ORC2, ORC3 and ORC4 stability.
分子量
85 kDa
基因ID
222229
UniProt
Q9UFC0
途径
Chromatin Binding
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