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KIF7 抗体

KIF7 适用: 人 WB, ELISA, IP 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7115710
发货至: 中国
  • 抗原 See all KIF7 抗体
    KIF7 (Kinesin Family Member 7 (KIF7))
    适用
    • 24
    • 16
    • 16
    • 2
    • 2
    • 2
    • 1
    宿主
    • 19
    • 5
    克隆类型
    • 19
    • 5
    多克隆
    标记
    • 13
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This KIF7 antibody is un-conjugated
    应用范围
    • 11
    • 10
    • 4
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunoprecipitation (IP)
    纯化方法
    Immunogen affinity purified
    纯度
    ≥95 % as determined by SDS-PAGE
    免疫原
    kinesin family member 7
    亚型
    IgG
    Top Product
    Discover our top product KIF7 Primary Antibody
  • 应用备注
    WB: 1:500-1:2000, IP: 1:500-1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    有效期
    12 months
  • 抗原
    KIF7 (Kinesin Family Member 7 (KIF7))
    别名
    KIF7 (KIF7 产品)
    别名
    KIF7 antibody, DDBDRAFT_0204609 antibody, DDBDRAFT_0206583 antibody, DDB_0204609 antibody, DDB_0206583 antibody, ACLS antibody, HLS2 antibody, JBTS12 antibody, UNQ340 antibody, cos2 antibody, costal2 antibody, kinesin family member 7 antibody, KIF7 antibody, kif7 antibody, Kif7 antibody
    背景
    Synonyms:KIF7, kinesin family member 7, Kinesin like protein KIF7, UNQ340 Background:Essential for hedgehog signaling regulation: acts as both a negative and positive regulator of sonic hedgehog(Shh) and Indian hedgehog(Ihh) pathways, acting downstream of SMO, through both SUFU-dependent and-independent mechanisms(PubMed:21633164). Involved in the regulation of microtubular dynamics. Required for proper organization of the ciliary tip and control of ciliary localization of SUFU-GLI2 complexes(By similarity). Required for localization of GLI3 to cilia in response to Shh. Negatively regulates Shh signaling by preventing inappropriate activation of the transcriptional activator GLI2 in the absence of ligand. Positively regulates Shh signaling by preventing the processing of the transcription factor GLI3 into its repressor form. In keratinocytes, promotes the dissociation of SUFU-GLI2 complexes, GLI2 nuclear translocation and Shh signaling activation(By similarity). Involved in the regulation of epidermal differentiation and chondrocyte development(By similarity).
    分子量
    150 kDa
    基因ID
    374654
    UniProt
    Q2M1P5
    途径
    Hedgehog Signaling
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