6030411N21Rik antibody, ABP-KELCH antibody, AU020744 antibody, Mav antibody, mKIAA4249 antibody, MAV antibody, MAYVEN antibody, kelch-like family member 2 antibody, kelch like family member 2 antibody, kelch-like 2, Mayven antibody, Klhl2 antibody, KLHL2 antibody
背景
Synonyms: Background:Component of a cullin-RING-based BCR(BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex that mediates the ubiquitination of target proteins, such as NPTXR, leading most often to their proteasomal degradation(By similarity). Responsible for degradative ubiquitination of the WNK kinases WNK1, WNK3 and WNK4. Plays a role in the reorganization of the actin cytoskeleton. Promotes growth of cell projections in oligodendrocyte precursors.