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IWS1 抗体

IWS1 适用: 人, 大鼠, 小鼠 WB, ELISA, IP 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7115537
发货至: 中国
  • 抗原 See all IWS1 products
    IWS1 (IWS1 Homolog (IWS1))
    适用
    • 17
    • 12
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 大鼠, 小鼠
    宿主
    • 17
    克隆类型
    • 16
    多克隆
    标记
    • 10
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This IWS1 antibody is un-conjugated
    应用范围
    • 10
    • 5
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunoprecipitation (IP)
    纯化方法
    Immunogen affinity purified
    纯度
    ≥95 % as determined by SDS-PAGE
    免疫原
    IWS1 homolog(S. cerevisiae)
    亚型
    IgG
  • 应用备注
    WB: 1:500-1:2000, IP: 1:200-1:2000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    有效期
    12 months
  • 抗原
    IWS1 (IWS1 Homolog (IWS1))
    别名
    IWS1 (IWS1 产品)
    别名
    1700069O15Rik antibody, 3000008H23 antibody, AL117927 antibody, AW214353 antibody, RGD1304762 antibody, IWS1, SUPT6H interacting protein antibody, IWS1, SUPT6 interacting protein antibody, IWS1 antibody, Iws1 antibody
    背景
    Synonyms:IWS1L Background:Transcription factor which plays a key role in defining the composition of the RNA polymerase II(RNAPII) elongation complex and in modulating the production of mature mRNA transcripts. Acts as an assembly factor to recruit various factors to the RNAPII elongation complex and is recruited to the complex via binding to the transcription elongation factor SUPT6H bound to the C-terminal domain(CTD) of the RNAPII subunit RPB1(POLR2A). The SUPT6H:IWS1:CTD complex recruits mRNA export factors(ALYREF/THOC4, EXOSC10) as well as histone modifying enzymes(such as SETD2) to ensure proper mRNA splicing, efficient mRNA export and elongation-coupled H3K36 methylation, a signature chromatin mark of active transcription.
    分子量
    116-120 kDa
    基因ID
    55677
    UniProt
    Q96ST2
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