Inversin 抗体
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- 抗原 See all Inversin (INVS) 抗体
- Inversin (INVS)
- 适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Inversin antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
- 纯化方法
- Immunogen affinity purified
- 纯度
- ≥95 % as determined by SDS-PAGE
- 免疫原
- inversin
- 亚型
- IgG
- Top Product
- Discover our top product INVS Primary Antibody
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anti-Inversin (INVS) (AA 1-101) antibody
INVS 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Inversin (INVS) (AA 1-91) antibodyINVS 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Inversin (INVS) (AA 1-90) antibodyINVS 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB: 1:500-1:2000, IHC: 1:20-1:200, IF: 1:20-1:200
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
- 有效期
- 12 months
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- 抗原
- Inversin (INVS)
- 别名
- INVS (INVS 产品)
- 别名
- invs-a antibody, INVS antibody, MGC140477 antibody, inv antibody, NPH2 antibody, NPHP2 antibody, INV antibody, Nphp2 antibody, RGD1563359 antibody, wu:fe47e11 antibody, inversin S homeolog antibody, inversin antibody, Inversin antibody, invs.S antibody, INVS antibody, Bm1_38710 antibody, PTRG_09181 antibody, EAMY_RS33690 antibody, LOAG_11716 antibody, invs antibody, Invs antibody
- 背景
- Synonyms:INV, NPHP2 Background:Required for normal renal development and establishment of left-right axis. Probably acts as a molecular switch between different Wnt signaling pathways. Inhibits the canonical Wnt pathway by targeting cytoplasmic disheveled(DVL1) for degradation by the ubiquitin-proteasome. This suggests that it is required in renal development to oppose the repression of terminal differentiation of tubular epithelial cells by Wnt signaling. Involved in the organization of apical junctions in kidney cells together with NPHP1, NPHP4 and RPGRIP1L/NPHP8(By similarity). Does not seem to be strictly required for ciliogenesis(By similarity).
- 分子量
- 110-115 kDa
- 基因ID
- 27130
- UniProt
- Q9Y283
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