9230116I04Rik antibody, 9430087H23Rik antibody, Pdzd6 antibody, Pdzk6 antibody, mKIAA1284 antibody, INT antibody, PDZD6 antibody, PDZK6 antibody, Xint antibody, in antibody, int antibody, pdzd6 antibody, inturned planar cell polarity protein antibody, inturned planar cell polarity protein S homeolog antibody, Intu antibody, INTU antibody, intu antibody, intu.S antibody
背景
Synonyms:KIAA1284, PDZD6, PDZK6 Background:Plays a key role in ciliogenesis and embryonic development. Regulator of cilia formation by controlling the organization of the apical actin cytoskeleton and the positioning of the basal bodies at the apical cell surface, which in turn is essential for the normal orientation of elongating ciliary microtubules. Plays a key role in definition of cell polarity via its role in ciliogenesis but not via conversion extension. Has an indirect effect on hedgehog signaling(By similarity).