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IL-17 抗体

This anti-IL-17 antibody is a 小鼠 单克隆 antibody detecting IL-17 in WB, ELISA 和 FACS. Suitable for 人.
产品编号 ABIN7115424
发货至: 中国

Quick Overview for IL-17 抗体 (ABIN7115424)

抗原

See all IL-17 (IL17) 抗体
IL-17 (IL17) (Interleukin 17 (IL17))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This IL-17 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Flow Cytometry (FACS)

克隆位点

5E2
  • 纯化方法

    Protein A+G purification

    纯度

    ≥95 % as determined by SDS-PAGE

    免疫原

    interleukin 17A

    亚型

    IgG1
  • 应用备注

    WB: 1:500-1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

    有效期

    12 months
  • 抗原

    IL-17 (IL17) (Interleukin 17 (IL17))

    别名

    IL-17

    背景

    Synonyms:CTLA 8, CTLA8, IL 17, IL 17A, IL17, IL-17, IL17A, interleukin 17A Background:IL17A, also named as IL-17, is a proinflammatory cytokine. IL-17, synthesized only by memory T cells and natural killer cells, has pleiotropic effects, mainly in the recruitment and activation of neutrophils. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2(PTGS2/COX-2), as well as enhance the production of nitric oxide(NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis. The IL-17 receptor is a type I transmembrane protein, that is widely expressed on epithelial cells, fibroblasts, B and T cells, and monocytic cells. In psoriatic skin lesions, both Th17 cells and their downstream effector molecules, e.g. IL-17 and IL-22, are highly increased.

    分子量

    18 kDa

    基因ID

    3605

    UniProt

    Q16552
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