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IMPA1 抗体

IMPA1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7115270
发货至: 中国
  • 抗原 See all IMPA1 抗体
    IMPA1 (Inositol(myo)-1(or 4)-Monophosphatase 1 (IMPA1))
    适用
    • 32
    • 13
    • 11
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 29
    • 3
    克隆类型
    • 30
    • 2
    多克隆
    标记
    • 14
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    This IMPA1 antibody is un-conjugated
    应用范围
    • 12
    • 6
    • 6
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)
    纯化方法
    Immunogen affinity purified
    纯度
    ≥95 % as determined by SDS-PAGE
    免疫原
    inositol(myo)-1(or 4)-monophosphatase 1
    亚型
    IgG
    Top Product
    Discover our top product IMPA1 Primary Antibody
  • 应用备注
    WB: 1:500 - 1:2000, IHC: 1:50 - 1:200, IF: 1:10 - 1:100
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3 ,
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    有效期
    12 months
  • 抗原
    IMPA1 (Inositol(myo)-1(or 4)-Monophosphatase 1 (IMPA1))
    别名
    IMPA1 (IMPA1 产品)
    别名
    zgc:100926 antibody, 2610002K09Rik antibody, 2900059K10Rik antibody, AI325909 antibody, IMP antibody, IMPA antibody, impa antibody, inositol monophosphatase 1 antibody, inositol(myo)-1(or 4)-monophosphatase 1 antibody, inositol (myo)-1(or 4)-monophosphatase 1 antibody, inositol monophosphatase antibody, inositol(myo)-1(or 4)-monophosphatase 1 S homeolog antibody, impa1 antibody, Impa1 antibody, IMPA1 antibody, impa1.S antibody
    背景
    Synonyms:IMPA Background:This gene encodes an enzyme that dephosphorylates myo-inositol monophosphate to generate free myo-inositol, a precursor of phosphatidylinositol, and is therefore an important modulator of intracellular signal transduction via the production of the second messengers myoinositol 1, 4, 5-trisphosphate and diacylglycerol. This enzyme can also use myo-inositol-1, 3-diphosphate, myo-inositol-1, 4-diphosphate, scyllo-inositol-phosphate, glucose-1-phosphate, glucose-6-phosphate, fructose-1-phosphate, beta-glycerophosphate, and 2'-AMP as substrates. This enzyme shows magnesium-dependent phosphatase activity and is inhibited by therapeutic concentrations of lithium. Inhibition of inositol monophosphate hydroylosis and subsequent depletion of inositol for phosphatidylinositol synthesis may explain the anti- manic and anti- depressive effects of lithium administered to treat bipolar disorder. Alternative splicing results in multiple transcript variants encoding distinct isoforms. A pseudogene of this gene is also present on chromosome 8q21.13.
    分子量
    30 kDa
    基因ID
    3612
    UniProt
    P29218
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