INO80 抗体
Quick Overview for INO80 抗体 (ABIN7115249)
抗原
See all INO80 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- INO80 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- INO80 homolog
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亚型
- IgG
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应用备注
- WB: 1:500-1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- INO80 (INO80 Homolog (INO80))
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别名
- INO80
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背景
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Synonyms: Chromatin-remodeling ATPase INO80 (hINO80)|DNA helicase-related INO80 complex homolog 1|DNA helicase-related protein INO80|INO80 complex subunit A|INO80|INO80A|INOC1|KIAA1259
Background: DNA helicase and probable main scaffold component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair, according to PubMed:20687897 the contribution to DNA double-strand break repair appears to be largely indirect through transcriptional regulation. Recruited by YY1 to YY1-activated genes, where it acts as an essential coactivator. Binds DNA. In vitro, has double-stranded DNA-dependent ATPase activity. Involved in UV-damage excision repair, DNA replication and chromosome segregation during normal cell division cycle.
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分子量
- 177, 150 kDa
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基因ID
- 54617
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UniProt
- Q9ULG1
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途径
- Positive Regulation of Response to DNA Damage Stimulus
抗原
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