IPO13 抗体
Quick Overview for IPO13 抗体 (ABIN7115209)
抗原
See all IPO13 抗体适用
宿主
克隆类型
标记
应用范围
-
-
纯化方法
- Immunogen affinity purified
-
纯度
- ≥95 % as determined by SDS-PAGE
-
免疫原
- importin 13
-
亚型
- IgG
-
-
anti-Importin 13 (IPO13) (C-Term) antibody
IPO13 适用: 人 WB, IP, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Importin 13 (IPO13) (AA 501-700) antibodyIPO13 适用: 人 ELISA, WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Importin 13 (IPO13) (AA 764-963) antibodyIPO13 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Importin 13 (IPO13) antibodyIPO13 适用: 人 ELISA, WB, IHC 宿主: 兔 unconjugated
-
-
应用备注
- WB: 1:500-1:2000, IHC: 1:20-1:200, IF: 1:20-1:200
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
-
有效期
- 12 months
-
-
- IPO13 (Importin 13 (IPO13))
-
别名
- IPO13
-
背景
- Synonyms:KIAA0724, RANBP13 Background:Functions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals(NLS) in cargo substrates. Is thought to mediate docking of the importin/substrate complex to the nuclear pore complex(NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP-and GDP-bound forms of Ran between the cytoplasm and nucleus(By similarity). Mediates the nuclear import of UBC9, the RBM8A/MAGOH complex, PAX6 and probably other members of the paired homeobox family. Also mediates nuclear export of eIF-1A, and the cytoplasmic release of eIF-1A is triggered by the loading of import substrates onto IPO13.
-
分子量
- 97kd
-
基因ID
- 9670
-
UniProt
- O94829
-
途径
- Intracellular Steroid Hormone Receptor Signaling Pathway, Nuclear Hormone Receptor Binding, Protein targeting to Nucleus
抗原
-
